Results 31 to 40 of about 109,408 (264)

PICO-based problem solving (question-answer) of the ST-segment elevation in the aVR lead in a patient with chest pain referred to a hospital emergency department: Letter to Editor

مجله دانشگاه علوم پزشکی بیرجند, 2022
In evidence-based medicine, constructing research questions is the most important part of research integration. Formulating a research question is the first step to conducting a credible and valuable research.
Ali MoeziBady, Mohammad Yousof Qoddusi, Nahid Azdaki, Nazanin Hanafi Bojd, Neda Partovi   +4 more
doaj  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Holistic Quality Evaluation, Selection and Improvement Approach driven by Multilevel Goals and Strategies

CLEI Electronic Journal, 2016
Organizations should establish business goals and check for their achievement in a systematic and disciplined way. In order to know if a business goal is achieved, it should be necessary to consider information need goals that also can require satisfying
Belen Rivera, Pablo Becker, Fernanda Papa, Luis Olsina   +3 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Applying an Improving Strategy that embeds Functional and Non-Functional Requirements Concepts

Journal of Computer Science and Technology, 2019
Organizations should set and reach business goals for varied purposes using the suitable strategies. Basically, a strategy specifies the activities, methods and another related resources that should be considered in order to achieve a given goal purpose.
Pablo Becker, Guido Tebes, Denis Peppino, Luis Olsina   +3 more
doaj   +1 more source

Wearable multimode sensor with a seamless integrated structure for recognition of different joint motion states with the assistance of a deep learning algorithm

Microsystems & Nanoengineering, 2022
Accurate motion feature extraction and recognition provide critical information for many scientific problems. Herein, a new paradigm for a wearable seamless multimode sensor with the ability to decouple pressure and strain stimuli and recognize the ...
Lei Wen, Meng Nie, Pengfan Chen, Yu-na Zhao, Jingcheng Shen, Chongqing Wang, Yuwei Xiong, Kuibo Yin, Litao Sun   +8 more
doaj   +1 more source

PICO-60 Results and PICO-40L Status

Journal of Physics: Conference Series, 2020
Abstract PICO-60 and PICO-40L are bubble chambers for dark matter searches that are using C3F8 as active liquid. PICO-60 was operated successfully at SNOLAB until 2017 and PICO-40L is now operating in the same location. PICO-40L follows a new detector concept that holds promise for future increases of sensitivity.
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

REHABILITACION DE SUELOS HORTÍCOLAS: IMPACTO DE PRÁCTICAS AGRÍCOLAS CON USO DE YESO Y DRENAJE

Fave: Sección Ciencias Agrarias, 2017
El exceso de Na + , carbonatos y bicarbonatos presentes en el agua de riego incrementan el pH, la conductividad eléctrica (CE) y el porcentaje de sodio intercambiable (PSI), afectando el crecimiento de los cultivos.
A. MUGUIRO, C. ÁLVAREZ, F. BABINEC, R. MARANO   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source