Results 71 to 80 of about 2,365 (200)

Long term treatment with stimulant laxatives:clinical evidence for effectiveness and safety?

, 2019
OBJECTIVES: Bisacodyl and sodium picosulfate are classified both as stimulant laxatives, approved for short-term treatment of constipation and sold without prescription (OTC).
Jimenez-Solem, Espen, Noergaard, Mia, Bring Christensen, Mikkel, Traerup Andersen, Jon   +3 more
core   +1 more source

Efficacy, safety, and tolerability of a ready-to-drink bowel preparation: subanalysis by age from a phase III, assessor-blinded study

Therapeutic Advances in Gastroenterology, 2020
Background: The incidence and mortality of colorectal cancer (CRC) increase with age and, therefore, it is recommended that adults undergo regular CRC screening, ideally by colonoscopy, with some new guidelines recommending screening begin at 45 years ...
Lawrence Hookey, Gerald Bertiger, Kenneth Lee Johnson, Mena Boules, Masakazu Ando, David N. Dahdal   +5 more
doaj   +1 more source

Drug Survival of Drugs Recommended for Irritable Bowel Syndrome: A Retrospective Observational Study

Neurogastroenterology &Motility, Volume 37, Issue 10, October 2025.
ABSTRACT Background There is limited data on how drugs prescribed for functional bowel disorders are re‐prescribed in clinical practice. This study aimed to investigate drug survival rates of different irritable bowel syndrome (IBS) treatments among patients referred to a gastroenterologist.
Alice Sandberg‐Janzon, Pontus Karling
wiley   +1 more source

Hyponatremic Coma after Bowel Preparation

European Journal of Case Reports in Internal Medicine, 2019
Introduction: Colonoscopy is a useful tool in modern medicine and is increasingly employed for both diagnostic and treatment purposes. However, bowel preparations can cause electrolyte imbalance, with the risk apparently related to the type of bowel ...
João Costelha, Rita Dias, Carla Teixeira, Irene Aragão   +3 more
doaj   +1 more source

Serious adverse events associated with bowel preparation for colonoscopy in Japan: Systematic review

Digestive Endoscopy, Volume 37, Issue 9, Page 905-918, September 2025.
Objectives Bowel preparation for colonoscopy can lead to serious adverse events (AEs), raising significant safety concerns in colorectal cancer (CRC) screening. A systematic review of these serious AEs in Japan was performed to explore potential management strategies.
Toshihiro Tadano, Koichiro Abe, Seiju Sasaki, Teruhiko Terasawa, Satoyo Hosono, Takafumi Katayama, Keika Hoshi, Tomio Nakayama, Chisato Hamashima   +8 more
wiley   +1 more source

Psychiatric‐onset neuronal intranuclear inclusion disease in a psychiatry‐based dementia‐enriched cohort in Japan

Psychiatry and Clinical Neurosciences, Volume 79, Issue 9, Page 561-571, September 2025.
Aim A GGC repeat expansion in the 5′ untranslated region of NOTCH2NLC is a genetic cause of Neuronal Intranuclear Inclusion Disease (NIID) that exhibits cognitive, motor, and autonomic dysfunction. Our objective is to determine whether there are undiagnosed NIID cases in a psychiatry‐based dementia‐enriched cohort and to identify their clinical ...
Tesshin Miyamoto, Kohji Mori, Shoshin Akamine, Shizuko Kondo, Shiho Gotoh, Ryota Uozumi, Sumiyo Umeda, Hanako Koguchi‐Yoshioka, Satoshi Nojima, Daiki Taomoto, Yuto Satake, Takashi Suehiro, Hideki Kanemoto, Kenji Yoshiyama, Takashi Morihara, Manabu Ikeda   +15 more
wiley   +1 more source

Bowel preparation and surgical site infections in laparoscopic and robot‐assisted right‐sided colon cancer surgery with intracorporeal anastomosis: A retrospective study

Annals of Gastroenterological Surgery, Volume 9, Issue 4, Page 711-718, July 2025.
This retrospective study investigated risk factors for surgical site infections (SSIs) in right‐sided colon cancer surgeries using intracorporeal anastomosis (IA). The results demonstrated that preoperative oral antibiotics (OA) significantly reduced SSI rates, with OA identified as an independent protective factor, suggesting its beneficial role in ...
Naoya Ozawa, Tomohiro Yamaguchi, Takumi Kozu, Tatsuki Noguchi, Takashi Sakamoto, Shimpei Matsui, Toshiki Mukai, Takashi Akiyoshi, Yosuke Fukunaga   +8 more
wiley   +1 more source

Evaluation of diuretic and laxative activity of aqueous extract of Argemone mexicana leaves in rats

Ars Pharmaceutica
Objectives: Argemone mexicana have been widely studied for its several pharmacological benefits and has been used in traditional medicine to treat constipation like symptoms.
Bairagi Shripad Motilal, Inayat B. Pathan, Nema Nitin   +2 more
doaj   +1 more source

The importance of colonoscopy bowel preparation for the detection of colorectal lesions and colorectal cancer prevention

Endoscopy International Open, 2020
Background and study aims Colonoscopy for colorectal cancer (CRC) screening has reduced CRC incidence and mortality and improved prognosis. Optimal bowel preparation and high-quality endoscopic technique facilitate early CRC detection.
Prateek Sharma, Carol A. Burke, David A. Johnson, Brooks D. Cash   +3 more
doaj   +1 more source

Efficacy and Safety of Linaclotide as an Adjunct to Polyethylene Glycol in Bowel Preparation: A Meta‐Analysis

Journal of Digestive Diseases, Volume 26, Issue 7-8, Page 318-333, July-August 2025.
Linaclotide combined with low‐volume polyethylene glycol (PEG) offers comparable bowel‐cleansing efficacy to traditional high‐volume PEG regimen while improving patient tolerability. Key benefits include higher segmental Boston Bowel Preparation Scale (BBPS) scores, reduced adverse events, and increased willingness to repeat the colonoscopic procedure,
Muhammad Shahzil, Fariha Hasan, Ali Akram Qureshi, Zainab Jamil, Talha Kashif, Muhammad Saad Faisal, Taha Bin Arif, Ammad Javaid Chaudhary, Umer Farooq, Hassam Ali, John M. Levenick   +10 more
wiley   +1 more source