Results 1 to 10 of about 6,229 (163)

Acetic acid-induced colitis modulating potential of total crude alkaloidal extract of Picralima nitida seeds in rats. [PDF]

Immun Inflamm Dis, 2023
The total crude alkaloidal extract of Picralima nitida seeds (PNE) is known to possess anti‐inflammatory activity among other therapeutic benefits although its benefits in colitis has not been investigated.
Otu-Boakye SA, Yeboah KO, Boakye-Gyasi E, Oppong-Kyekyeku J, Okyere PD, Osafo N.   +5 more
europepmc   +3 more sources

Purification of aquaculture effluent using Picralima nitida seeds. [PDF]

Sci Rep, 2022
AbstractAquaculture effluent treatment is essential to eliminate the undesirable characteristics of water to ensure cleaner production and environmental sustainability. In an effort to develop green coagulant without compromising cost, this research investigated the feasibility of aquaculture effluent (AQEF) pollutant removal usingPicralima nitidaseeds
Igwegbe CA, Ovuoraye PE, Białowiec A, Okpala COR, Onukwuli OD, Dehghani MH.   +5 more
europepmc   +5 more sources

Isolation and Pharmacological Characterization of Six Opioidergic Picralima nitida Alkaloids. [PDF]

J Nat Prod, 2021
The seeds of the akuamma tree (Picralima nitida) have been used as a traditional treatment for pain and fever. Previous studies have attributed these effects to a series of indole alkaloids found within the seed extracts; however, these pharmacological studies were significantly limited in scope. Herein, an isolation protocol employing pH-zone-refining
Creed SM, Gutridge AM, Argade MD, Hennessy MR, Friesen JB, Pauli GF, van Rijn RM, Riley AP.   +7 more
europepmc   +5 more sources

In vivo anthelmintic potentials of Gongronema latifolium and Picralima nitida against gastrointestinal parasite (Heligmosomoides bakeri). [PDF]

Helminthologia, 2023
Summary Gastrointestinal parasites which are responsible for soil-transmitted helminthiases cause illness globally. The control of helminthiasis depends on mass distribution of anthelmintics which has been reported for its resistance, toxicity and low ...
Ojo FT, Idowu OA, Ademolu KO, Olukunle JO.   +3 more
europepmc   +2 more sources

Antioxidant and Antimalarial Activities of Methanol Extract of Picralima nitida Root Bark

Journal of Applied Sciences and Environmental Management, 2023
Ethnomedically, the root, stem bark, seed or leaves of Picralima nitida are relevant in local preparations as antimalaria, antipyretic, antihypertensive and gastrointestinal agents. This study was therefore designed to determine the antimalarial and antioxidant effects of the methanol extract of the root bark of Picralima nitida using standard ...
O. Erharuyi, A. O. Eze, V. O. Imieje, S. E. Aghahowa, A. Falodun   +4 more
openaire   +4 more sources

Selected Preclinical Studies on Picralima nitida Stem Bark Extract

Tropical Journal of Drug Research
Purpose: Traditional medicine has utilized Picralima nitida (Apocynaceae) to treat a variety of illnesses, including microbial and pain-induced infections, diabetes, inflammation, and malaria. Methods: The phytochemical screening, haematological, and histological studies were carried out using already established methods.
Osahon K. Ogbeide, Onome Sajere, Nelson Omorefe, O. N. Aghedo, Joshua I. Isibor, O. Osarinmwian, Jeremiah O. Uadia, Osaro Iyekowa   +7 more
openaire   +2 more sources

Antiplasmodial and anti-trypanosomial monoterpene indole alkaloids from Picralima nitida

Natural Product Research
Eight monoterpene indole alkaloids (1–8), including one new picraline-type alkaloid, 2-hydroxyakuammiline (4) and seven known compounds: akuammigine (1), akuammine (2), akuammidine (3), akuammiline (5a), akuammiline N-oxide (5b), akuammiline (6), rhazimol (7), and alstonine (8) were isolated from the seeds of Picralima nitida. Structure elucidation was
Michael Konney, Laryea, Kofi Mensah Wonder, Abotsi, Eric, Woode, Rita Akosua, Dickson, Lauren, Webster, Edmund, Ekuadzi   +5 more
openaire   +3 more sources

Antidepressant-like effect of picralima nitida total crude alkaloidal fraction in mice

Scientific African
In 2019, WHO, reported that an estimate of 350 million people globally have depression. Despite the advances made in current pharmacotherapy, about 30–40 % of patients receive insufficient treatment because of the increased occurrence of partial or non-response as well as delayed onset of antidepressive action. Herbs, however, offer a vital solution to
Prince Dagadu Okyere, Christian Chukwuma Ndu, Donatus Wewura Adongo, Charles Kwaku Benneh, Eric Woode, Edmund Ekuadzi, Wonder Kofi Mensah Abotsi, Eric Boakye-Gyasi, Priscilla Kolibea Mante   +8 more
openaire   +3 more sources

Anti-Inflammatory Activity of the Stem Bark Methanol Extract of Picralima nitida

European Journal of Medicinal Plants, 2021
Aims: To investigate the anti-inflammatory activity of Picralima nitida stem bark methanol extract (PNSBE). Study Design: The study was carried out using in vivo (carrageenan-induced paw oedema and egg albumin-induced paw oedema) and in vitro (Human red blood cell (HRBC) membrane stabilization assay) models in rat. Place and Duration of ...
K. K. Igwe, M. I. Ezeja, O. V. Ikpeazu
openaire   +3 more sources

Larvicidal And Antifungal Properties Of Picralima Nitida (Apocynaceae) Leaf Extracts [PDF]

European Journal of Medicinal Plants, 2012
The larvicidal and antifungal activities of ethanolic and aqueous leaf extracts of Picralima nitida were evaluated in static bioassays on 4th instar larvae of Anopheles gambiae and three fungal species: Aspergillus flavus, Candida albicans and Microsporum canis. All extractions were done using distilled water and 50% ethanol.
Ubulom Peace M., E., Imandeh N. G. , Udobi Chinweizu E. , IIya Ibrahim   +3 more
openaire   +2 more sources