Results 101 to 110 of about 6,229 (163)

Toxicological evaluation of Picralima nitida in rodents

Journal of Ethnopharmacology, 2019
Picralima nitida (Stapf) T. Durand and H. Durand (Apocynaceae), over the years has shown wide range of usage in African folk medicine and its safety profile in instances of prolonged use and pregnancy are major concerns. The study aimed to extensively investigate the toxicological effects of Picralima nitida in albino rodents and make appropriate ...
Olufunsho, Awodele, Abdul Gafar Victoir, Coulidiaty, Gbenga Oluyemi, Afolayan, Sunday, Agagu, Bunmi, Omoseyindemi, Kofi, Busia   +5 more
openaire   +2 more sources

Biotransformation of the secondary metabolites from Picralima nitida and their antibacterial activities

Phytochemistry Letters
F.D. Mabou, I. Rouaud, S. Ferron, A. Sauvager, L. Bousarghin, D. Ngnokam, S. Tomasi   +6 more
openaire   +2 more sources

Phytochemical, Proximate Composition, Mineral, Antioxidant, and Radical Scavenging Capacity of Picralima nitida Fruit Pulp Aqueous Extract

Nigerian Journal of Basic and Applied Sciences
Picralima nitida (Apocynaceae) is widely known for its efficacy in ameliorating the discomfort associated with different diseases. The  objective of this research is to investigate the phytochemicals, proximate composition, antioxidant, and antioxidant ...
J.O. Ilenowa, O. O. Ogedengbe, H. Oboh
semanticscholar   +1 more source

Gene expression of ifn- gamma and icam-1 in benzene induced haematotoxicity bearing wistar rats treated with a bi- herbal mixture of Picralima nitida and Cymbopogon citratus extract

Dutse Journal of Pure and Applied Sciences
Picralima nitida and Cymbopogon citratus, commonly used in traditional medicine for their health benefits, have gained interest due to their bioactive compounds with anti-inflammatory properties, offering potential for new therapeutic applications ...
Obazelu P. A., Osarinmwian I.
semanticscholar   +1 more source

THE HYPOGLYCEMIC PROPERTIES OF PICRALIMA NITIDA

Nigerian Journal of Natural Products and Medicine, 1999
The extract of Picralima nitida effects hypoglycemia in both normal and alloxanized diabetic rabbits by a mechanism independent of the availability of insulin from pancreatic β-cell. Key Words: Picralima nitida, Apocynaceae, hypoglycemia, mice, rabbit. Nig. J. Nat Prod. And Med.
openaire   +2 more sources

In Vitro Assessment of Picralima nitida Ethanol Leaf Extract's Ability to Inhibit alpha-Amylase and alpha-Glucosidase Enzymes.

Journal of physical chemistry and functional materials
This study investigated the in vitro α-amylase and α-glucosidase inhibitory activities of the n-hexane and chloroform fractions of Picralima nitida ethanol leaf extract, comparing them with acarbose, a standard antidiabetic drug.
Okeke Chibuzor Okechukwu, Ikenna Nnaoma, R. Joseph, Robinson Nwabueze Oguebie   +3 more
semanticscholar   +1 more source

Regulatory Activity of the Aqueous Extract of Picralima nitida Seeds (Apocynaceae) on the Glycemia of Normoglycemic and Hyperglycemic Wistar Rats

Journal of Advances in Biology & Biotechnology
Picralima nitida is a plant commonly used in traditional African medicine for its antimalarial, antidiuretic, antidiarrheal, anti-inflammatory and antioxidant effects.
B. Landry, K. John, Ouattara-Soro Fatou Shcherazade   +2 more
semanticscholar   +1 more source

Evaluation of the in vitro antimalarial activity of Picralima nitida extracts

Journal of Ethnopharmacology, 1992
Extracts of Picralima nitida seeds, fruit rind, and stem bark have been investigated in vitro for antimalarial activity. The extracts showed remarkable inhibitory activity against drug resistant clones of Plasmodium falciparum at doses of 1.23-32 micrograms/ml.
M M, Iwu, D L, Klayman
openaire   +2 more sources

PHYTOCHEMICAL COMPOSITION, ANTIBACTERIAL ACTIVITY, PROXIMATE AND MINERAL ANALYSIS OF METHANOL EXTRACT FROM COMBINED SEEDS AND PEELS OF PICRALIMA NITIDA

Universal Journal of Pharmaceutical Research
Background and Aim: This study explores the untapped potential of the discarded seed and peel of Picralima nitida, a plant with numerous ethno-medicinal uses.
P. O. Alaebo, N. Achi, P. U. Ezurike, Anthony Cemaluk, Chinedum Egbuonu, C. Nwuke, Enyinna Wisdom Chukwuka, A. Onochie, Favour Junior Abuchi   +8 more
semanticscholar   +1 more source

PHYTOCHEMICAL-ASSISTED SYNTHESIS OF IRON OXIDE NANOPARTICLES FROM PICRALIMA NITIDA STEM BARK: STRUCTURAL CHARACTERIZATION AND ANTIOXIDANT PROPERTIES

Acta Scientifica Malaysia
This study reports the green synthesis of iron oxide nanoparticles (FeONPs) using Picralima nitida stem bark extract, a plant renowned for its rich phytochemical profile.
Aghedo, Oscar Notoriuwa, Ogbeide, Osahon Kennedy, Imafidon, Monday Idiaghe, Iyekowa Osaro   +6 more
semanticscholar   +1 more source