Protective Role of Picralima nitida Seed Extract in High-Fat High-Fructose-Fed Rats. [PDF]
Adv Pharmacol Pharm Sci, 2020 Picralima nitida is a therapeutic herb used in ethnomedicine for the management of several disease conditions including diabetes. This study examined the potential palliative effect of aqueous seed extract of Picralima nitida (APN) on dyslipidemia, hyperglycemia, oxidative stress, insulin resistance, and the expression of some metabolic genes in high ...
De Campos OC +5 more
europepmc +2 more sources
The Antiplasmodial Potential of Medicinal Plants Used in the Cameroonian Pharmacopoeia: An Updated Systematic Review and Meta-Analysis. [PDF]
Evid Based Complement Alternat Med, 2022 Malaria is a real public health problem. It is the leading cause of morbidity and mortality in the world. Research in herbal medicine has so far shown that the use of plants against malaria is not to be neglected. This review aims to highlight the antiplasmodial potential of Cameroonian plants.
Tepa AGN +4 more
europepmc +2 more sources
Acute and Subchronic Toxicity Studies on the Aqueous Extract of the Plant Mixture (Bidens pilosa and Cymbopogon citratus Aerial Parts) in Rat Model. [PDF]
J Toxicol, 2022 Bidens pilosa (B. pilosa) and Cymbopogon citratus (C. citratus) are plants used individually or in combination in the traditional treatment of several ailments such as cardiovascular disorders. In order to valorise their traditional use, a toxicological study was conducted on the aqueous extract of the mixture of aerial parts of B.
Tcheutchoua YC +10 more
europepmc +2 more sources
The Activity of Plant Crude Extracts against Schistosoma mansoni. [PDF]
J Parasitol Res, 2021 Background. Schistosoma mansoni remains a significant health problem in low‐income countries. Praziquantel (PZQ) is the only drug available to treat schistosomiasis, and PZQ resistance is a potential threat towards control of the disease although PZQ is currently effective against all species of schistosomes.
Basha H, Mamo H.
europepmc +2 more sources
Exploring Medicinal Plants for Antimicrobial Activity and Synergistic Effects With Doxycycline Against Bacterial Species. [PDF]
ScientificWorldJournalMedicinal plants are rich sources of bioactive compounds with diverse pharmacological properties, including antimicrobial activities. This study aimed to assess the antibiofilm potential of methanol and ethanol extracts from nine selected medicinal plants, as well as their synergistic effects with doxycycline against Bacillus strains.
Kenmeni JF +5 more
europepmc +2 more sources
Evaluation of Antimalarial Potential of Extracts from Alstonia boonei and Carica papaya in Plasmodium berghei-Infected Mice. [PDF]
Evid Based Complement Alternat Med, 2021 Extracts of Alstonia boonei and Carica papaya are used in herbal medicine for the treatment of malaria. This work investigated the phytochemical, antioxidant, and antimalarial effects of hydromethanolic extracts of Alstonia boonei and Carica papaya.
Atanu FO +5 more
europepmc +2 more sources
Journal of Parasitology Research, Volume 2023, Issue 1, 2023., 2023 This study focused on documenting and evaluating the cercaricidal activity of medicinal plants used for schistosomiasis treatment in an endemic area in Ghana. Through semistructured questionnaires, personal interviews with herbalists in communities surrounding the Barekese dam in the Atwima‐Nwabiagya district, where the disease is endemic, were carried
Evelyn Asante-Kwatia +7 more
wiley +1 more source
Alpha-Amylase Inhibition and Antioxidative Capacity of Some Antidiabetic Plants Used by the Traditional Healers in Southeastern Nigeria. [PDF]
ScientificWorldJournal, 2017 Oxidative stress plays a significant role in the pathogenesis of metabolic syndrome including diabetes mellitus (DM). The inhibition of alpha‐amylase is an important therapeutic target in the regulation of postprandial increase of blood glucose in diabetic patients.
Oyedemi SO +5 more
europepmc +2 more sources
Opioid activity of alkaloids extracted from Picralima nitida (fam. Apocynaceae)
European Journal of Pharmacology, 1998 Extracts of the seeds of Picralima nitida (fam. Apocynaceae) have been reported to have opioid analgesic activity. In this investigation, isolated tissue bioassays and radioligand binding assays have been used to determine the opioid activity of five alkaloids--akuammidine, akuammine, akuammicine, akuammigine and pseudoakuammigine--extracted from the ...
J R, Menzies +3 more
openaire +6 more sources
Natural Products as Sources of Antimalarial Drugs: Ethnobotanical and Ethnopharmacological Studies
Scientifica, Volume 2020, Issue 1, 2020., 2020 Ethnopharmacological Relevance. Malaria is one of the lethal diseases of man, contributing to about 17 million deaths annually, leading to sociocultural, economic, and health influences. Aim of the Study. The study explores the ethnobotanical and ethnopharmacological appraisal of antimalarial plants used by people of Omu Aran, Ogbomoso, Ado Ekiti, and ...
Oluwole Solomon Oladeji +4 more
wiley +1 more source