Results 111 to 120 of about 329 (142)

Inhibition of CYP450 enzymes by quassinoids from Picrasma quassioides leaves

Phytochemistry Letters, 2019
Abstract Three new C20 quassinoids, namely, nigakilactones R (1), S (2), and T (3), along with 13 known ones, were isolated on Picrasma quassioides leaves. Their structures were elucidated by an extensive spectroscopic analysis. All the compounds were tested for their inhibitory activities against the six major CYP450 enzymes CYP1A2, 2C8, 2C9, 2C19 ...
Chang Liu, Rong-Rong Cheng, Li Yang, Zhong-Chen Song, Zheng-Tao Wang   +4 more
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Production of the triterpenoid quassin in callus and cell suspension cultures of Picrasma quassioides Bennett

Plant Cell Reports, 1986
Plant cell and suspension cultures have been established from stem cuttings of Picrasma quassioides Bennett. The effect of 244 different types/concentrations of plant growth regulators on growth and quassin accumulation in callus tissue was investigated.
A H, Scragg, E J, Allan
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Effects of Picrasma quassioides and its active constituents on Alzheimer's disease in vitro and in vivo

Bioorganic Chemistry, 2019
Alzheimer disease (AD), a prevalent neurodegenerative disorder, is one of the leading causes of dementia. However, there is no effective drug for this disease to date. Picrasma quassioides (D.Don) Benn, a Chinese traditional medicine, was used mainly for the treatment of inflammation, fever, microbial infection and dysentery. In this paper, we reported
Eryan, Guo, Yunwei, Hu, Tao, Du, Huilin, Zhu, Lei, Chen, Wei, Qu, Jie, Zhang, Ning, Xie, Wenyuan, Liu, Feng, Feng, Jian, Xu   +10 more
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ChemInform Abstract: Antiinflammatory Alkaloids from the Stems of Picrasma quassioides Bennet.

ChemInform, 2011
AbstractSeven new β‐carboline alkaloids (I) and (II) are isolated from the anti‐inflammatory CHCl3‐soluble fraction.
Wei‐Hua Jiao, Hao Gao, Feng Zhao, Hou‐Wen Lin, Yu‐Min Pan, Guang‐Xiong Zhou, Xin‐Sheng Yao   +6 more
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Tobacco Mosaic Virus (TMV) Inhibitors from Picrasma quassioides Benn

Journal of Agricultural and Food Chemistry, 2009
To investigate natural inhibitors against tobacco mosaic virus (TMV) from plants, 10 known beta-carboline alkaloids and one quassinoid have been isolated from MeOH extract of the wood of Picrasma quassioides Benn. These compounds were screened for their inhibitory activities against tobacco mosaic virus (TMV).
Jia, Chen, Xiao-Hui, Yan, Jia-Hong, Dong, Peng, Sang, Xin, Fang, Ying-Tong, Di, Zhong-Kai, Zhang, Xiao-Jiang, Hao   +7 more
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Phenylpropanoids and other secondary metabolites from fresh fruits of Picrasma quassioides

Phytochemistry, 1995
Four new constituents; two benzofuran glucosides (picraquassiosides A and B), a neolignan (picraquassioside C) and a phenol (picraquassioside D) were isolated from fresh fruits of Picrasma quassioides, together with seven known compounds. The structures of the new compounds were elucidated as 6-hydroxy-4-methoxy-5-benzofuran-propionic acid 6-O-β-d ...
Kazuko Yoshikawa, Saori Sugawara, Shigenobu Arihara   +2 more
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Five New Quassinoids from the Bark of Picrasma quassioides

Helvetica Chimica Acta, 2004
AbstractFive new quassinoids, named picraqualides A–E (1–5), together with eleven known ones, nigakilactone E (6), nigakilactone F (7), kusulactone (8), javanicin U (9), 12‐norquassin (10), quassin (11), 2,3‐didehydropicrasin B (12), nigakilactone B (13), nigakilactone C (14), picrasin B (15), and simalikalacton C (16), were isolated from the EtOH ...
Sheng‐Ping Yang, Jian‐Min Yue
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Picrasma quassioides leaves: Insights from chemical profiling and bioactivity comparison with stems

Fitoterapia
In Chinese Pharmacopeia, Picrasma quassioides (PQ) stems and leaves are recorded as Kumu with antimicrobial, anti-cancer, anti-parasitic effects, etc. However, thick stems are predominantly utilized as medicine in many Asian countries, with leaves rarely used. By now, the phytochemistry and bioactivity of PQ leaves are not well investigated.An Orbitrap
Haibo, Hu, Bin, Hu, Changling, Hu, Yingli, Zhu, Runan, Zhang, Hang, Qiu, Hao, Huang, Walter, Luyten   +7 more
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Quassidines A−D, Bis-β-carboline Alkaloids from the Stems of Picrasma quassioides

Journal of Natural Products, 2010
Four new bis-beta-carboline alkaloids, quassidines A-D (1-4), together with a known alkaloid, picrasidine C (5), were isolated from the stems of Picrasma quassioides. Quassidine A (1) is the first reported bis-beta-carboline alkaloid possessing a novel cyclobutane moiety.
Wei-Hua, Jiao, Hao, Gao, Chen-Yang, Li, Feng, Zhao, Ren-Wang, Jiang, Ying, Wang, Guang-Xiong, Zhou, Xin-Sheng, Yao   +7 more
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Aromatic glycosides and lignans glycosides with their acetylcholinesterase inhibitory activities from the leaves of Picrasma quassioides

Fitoterapia
In this study, eight new natural products were isolated from the leaves of Picrasma quassioides. Spectroscopic techniques were used for the elucidation of their planar structures. Their absolute configurations were elucidated on the basis of electron circular dichroism (ECD) techniques combined with the P/M helicity rule for the 2,3-dihydrobenzofuran ...
Qi, Jia, Pei-Yuan, Yang, Xin, Zhang, Shao-Jiang, Song, Xiao-Xiao, Huang   +4 more
openaire   +2 more sources