Background: Percutaneous collagen induction (PCI) through dermal roller breaks old collagen strands, promotes removal of damaged collagen and induces more collagen formation.
Fatma El-Zahraa Salah El-Deen Yassin +2 more
doaj +1 more source
Gender differences in cardiac left ventricular mass and function: clinical and experimental observations [PDF]
Background: The aim of this study was to evaluate gender-associated impact on left ventricular mass (LVM) and on left ventricular function (LVF) in humans and rats with aging. Methods: Myocyte area and collagen volume fraction (CVF) were studied in rats.
Aiello, Ernesto Alejandro +5 more
core +2 more sources
Collagen fibers in oral submucous fibrosis - A polarizing microscopy study using two special stains
Background: Oral submucous fibrosis (OSMF), a well-recognized oral potentially malignant disorder, results due to increased collagen production and reduced collagen degradation.
Roquaiya Nishat, Harish Kumar
doaj +1 more source
Idiopathic noncirrhotic portal hypertension: current perspectives [PDF]
The term idiopathic noncirrhotic portal hypertension (INCPH) has been recently proposed to replace terms, such as hepatoportal sclerosis, idiopathic portal hypertension, incomplete septal cirrhosis, and nodular regenerative hyperplasia, used to describe ...
D'AMATI, Giulia +5 more
core +1 more source
Biological Behavior of Xenogenic Scaffolds in Alcohol-Induced Rats: Histomorphometric and Picrosirius Red Staining Analysis [PDF]
In this experimental protocol, the objective was to evaluate the biological behavior of two xenogenic scaffolds in alcohol-induced rats through histomorphometric and Picrosirius Red staining analysis of non-critical defects in the tibia of rats submitted or not to alcohol ingestion at 25% v/v. Eighty male rats were randomly divided into four groups (n =
Dayane Maria Braz Nogueira +17 more
openaire +2 more sources
The impact of SPARC on age-related cardiac dysfunction and fibrosis in Drosophila [PDF]
Tissue fibrosis, an accumulation of extracellular matrix proteins such as collagen, accompanies cardiac ageing in humans and this is linked to an increased risk of cardiac failure.
Hartley, Paul S. +3 more
core +1 more source
Combined therapeutic benefit of mitochondria-targeted antioxidant, MitoQ10, and angiotensin receptor blocker, losartan, on cardiovascular function [PDF]
<b>Objective:</b><p></p> Mitochondria-derived reactive oxygen species (ROS) play important roles in the development of cardiovascular disease highlighting the need for novel targeted therapies.
Adlam +41 more
core +1 more source
Histological and immunohistochemical evaluation of two cell therapy protocols in equine suspensory ligament repair [PDF]
This study aimed to histologically evaluate the quality of tissue repair in equine suspensory ligament treated with two cell therapy protocols. All four limbs of six animals were operated simultaneously to remove a fragment in each ligament using a skin ...
L.C. Garbin +5 more
doaj +1 more source
Abstract Traditional methodologies for fibrosis quantification involve histological measurements, staining with Masson’s trichrome and picrosirius red (PSR), and label-free imaging using second harmonic generation (SHG). The difficulty of label-free cardiac SHG imaging is that both collagen (i.e., collagen 1 fibrils) and myosin are ...
Jones, Bryce A. +7 more
openaire +2 more sources
Role of the protein annexin A1 on the efficacy of anti-TNF treatment in a murine model of acute colitis [PDF]
TNF-α is involved in the mechanisms that initiate inflammatory bowel diseases (IBDs). Anti-TNF-α drugs, such as infliximab (IFX), cause non-responsiveness and side effects, indicating the need to investigate alternative therapies for these diseases.
Barrios, Bibiana Elisabet +6 more
core +1 more source

