Results 51 to 60 of about 3,539,899 (186)

Picrosirius‐Polarization Method for Collagen Fiber Detection in Tendons: A Mini‐Review

Orthopaedic Surgery, 2021
Although the structure and composition of collagen have been studied by polarized light microscopy since the early 19th century, many studies and reviews have paid little or no attention to the morphological problems of histopathological diagnosis.
Jie Liu, Ming‐you Xu, Jing Wu, Hao Zhang, Li Yang, Deng‐xing Lun, Yong‐cheng Hu, Bin Liu   +7 more
doaj   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

Advanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang, Xueting Huang, Lingxiao Yang, Jin Liu, Lei Lei, Shaomin Zou, Kai Wang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

Biomimetic Gradient Hydrogels Regulate Osteochondral Regeneration Microenvironment Remodeling via Spatiotemporal Programming Engineering

Advanced Science, EarlyView.
Electric field‑driven continuous gradient hydrogel GHZF4 achieves spatiotemporal growth factor release, modulates immune microenvironment, angiogenesis and osteochondral differentiation. It realizes cell‑free functional osteochondral repair in rat/rabbit models, offering a promising biomimetic strategy for gradient tissue regeneration.
Xiaolian Niu, Shengzhao Xiao, Di Huang, Xuesong Wang, Yanwei Cao, Xiaodan Sun, Nicholas Dunne, Xiaoming Li   +7 more
wiley   +1 more source

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

Example pictures of picrosirius red staining under polarized light of both study groups on day 60.

, 2015
Example pictures of picrosirius red staining under polarized light of both study groups on day 60.
Bohdan Pomahac (407566), Sebastian Fischer (553780), Christoph Hirche (766635), Jurij Kiefer (766637), Ulrich Kneser (484321), Muayyad Alhefzi (766640), Ericka M. Bueno (407565), Matthias A. Reichenberger (766636), Yannick Diehm (766638), Srinivasan Mukundan Jr. (766639)   +9 more
core   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Myocyte Diameter and Picrosirius Red Staining of 4-month old Fabry KO and WT mice.

, 2012
Myocyte Diameter and Picrosirius Red Staining of 4-month old Fabry KO and WT mice.
Frederic Jaisser (120606), Vincent Agrapart (166472), David G. Warnock (166505), Wenguang Feng (157190), Edgar Jaimes (166498), Brigitte Escoubet (166463), Trenton Schoeb (166487), Aurelie Nguyen Dinh Cat (166454), Violaine Griol-Charhbili (166481)   +8 more
core   +1 more source

Liver biopsy quality criteria to exclude cirrhosis in case of suspicion of porto-sinusoidal vascular disorder

JHEP Reports
Background & Aims: Baveno VII guidelines based porto-sinusoidal vascular disorder (PSVD) diagnosis on a liver biopsy excluding cirrhosis. However, evidence-based quality criteria for liver biopsy are lacking.
Chloé de Broucker, Valérie Paradis, Maria Luisa Botero, Miguel Albuquerque, Audrey Payancé, Aurélie Plessier, Laure Elkrief, François Durand, Sophie Hillaire, Paul-Emile Zafar, Juan Carlos Garcia Pagan, Pierre-Emmanuel Rautou   +11 more
doaj   +1 more source

An experimental model for the study of collagen fibers in skeletal muscle Modelo experimental para o estudo de fibras de colágeno no músculo esquelético

Acta Cirúrgica Brasileira, 2012
PURPOSE: To examine histological and histomorphometric techniques for measuring collagen in skeletal muscle. METHODS: The following staining methods were used in the study: hematoxylin and eosin, Masson's trichrome, reticulin, and picrosirius red, and ...
Eliziane Nitz de Carvalho Calvi, Fábio Xerfan Nahas, Marcus Vinícius Barbosa, José Augusto Calil, Silvia Saiuli Miki Ihara, Marcelo de Souza Silva, Marcello Fabiano de Franco, Lydia Masako Ferreira   +7 more
doaj   +1 more source