Results 41 to 50 of about 13,325 (181)

Assessment of Changes in Birefringence and Orientation of Collagen Fibres in Different Grades of Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma using Picrosirius Red and Polarising Microscopy [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Oral Submucous Fibrosis (OSMF) is a potentially malignant disease with a prevalence of 7-13%. It is characterised by the fibroelastic changes due to excessive deposition of collagen which results in dense fibrous bands and epithelial ...
Ashwini Chikkanayakanahalli Prabhakar, HC Girish, Varsha Vimal Kumar, Umapathy Thimmegowda , Praveen Mallavalli Nagaraj Shetty   +4 more
doaj   +1 more source

Image analyses of collagen types and thickness in oral sub mucous fibrosis stained with picrosirius red under polarizing microscope

Journal of Orofacial Sciences, 2013
Context: Oral submucous fibrosis (OSF) is a potentially malignant oral disorder leading to increased fibrosis in the sub-epithelial layer. The collagen in the condition has been a subject of intense scrutiny in an attempt to understand the pathogenesis ...
Venkatesh V Kamath, Krishnanand Satelur, Y Komali, Shruthi S Krishnamurthy   +3 more
doaj   +1 more source

Analysis of collagen fibers in keratocystic odontogenic tumor and ameloblastoma: A polarizing microscopic study

Indian Journal of Dental Research, 2019
Introduction: Collagen forms an integral part of connective tissue and maintains its structural integrity. It has natural birefringence which is attributed to the arrangement of its fibers and is enhanced by special stains such as picrosirius red through
Kalavani Peddapelli, Venkateswara Rao, Manchikatla Praveen Kumar, Taneeru Sravya, Dumpala Rakesh   +4 more
doaj   +1 more source

Human acellular amniotic membrane scaffolds encapsulating juvenile cartilage fragments accelerate the repair of rabbit osteochondral defects

Bone & Joint Research, 2022
Aims: The purpose of this study was to explore a simple and effective method of preparing human acellular amniotic membrane (HAAM) scaffolds, and explore the effect of HAAM scaffolds with juvenile cartilage fragments (JCFs) on osteochondral defects ...
Zhang Jun, Wang Yuping, Huang Yanran, Liu Ziming, Li Yuwan, Zhu Xizhong, Wu Zhilin, Luo Xiaoji   +7 more
doaj   +1 more source

The polarization colors of picrosirius red-stained collagen in systemic sclerosis.

Nishi Nihon Hifuka, 1991
全身性鞏皮症における真皮膠原線維の変化を知るために, Picrosirius red染色標本を偏光顕微鏡にて観察した。皮膚片は15例の全身性鞏皮症患者(浮腫∼硬化期2例, 硬化期11例, 萎縮期2例)の前腕伸側から得られた。また, 健康人27例より得た材料を対照とした。その結果, 健康人では年齢, 性, 部位にかかわりなく同じ橙色偏光を示した。これに対し鞏皮症にあつては, 病期と関係なしにすべて緑色偏光を示すのが観察された。一部についておこなわれた電顕的観察では, 鞏皮症における膠原線維の直径は, 健康人のそれに比較して小さいのが認められた。これらより偏光の違いには膠原線維の直径が関与し, そしてこの方法が鞏皮症の病理組織学的診断に有用であることが示唆される。
Nobuhiro YAMAMOTO, Mamoru KASADA, Yoichiro SASAI   +2 more
openaire   +2 more sources

Polarized microscope assisted study of collagen fibres in Oral Submucous Fibrosis and their clinicopathologic correlation: An in-vitro study

Journal of Oral Biology and Craniofacial Research, 2018
Background: The present study was aimed to evaluate and analyze orientation and birefringence pattern of collagen fibers histopathologically in different grades of OSMF using the special stain (Picrosirius red) under polarizing microscope and relate ...
Ameena Singh, Sukumar Singh, Susmita Saxena, Sanjeev Kumar, Akanksha Banga, Nitin Purohit   +5 more
doaj   +1 more source

Quantitative Insights into Collagen in Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma using Picrosirius Red Stain [PDF]

Dental Journal of Advance Studies
Context: One of the predominant forms of cancer found in the oral cavity is squamous cell carcinoma. According to the records of the National Cancer Registry Programme, squamous cell carcinoma is the leading type of cancer affecting both men and women in
Kanika Sharma, Radheshyam Singh, Sumit S Sinha, Paramjit Singh, Neeraj Grover, Sanjeet Singh   +5 more
doaj   +1 more source

Fibrosis quantification using multiphoton excitation imaging of picrosirius red stained cardiac tissue

, 2023
Abstract Traditional methodologies for fibrosis quantification involve histological measurements, staining with Masson’s trichrome and picrosirius red (PSR), and label-free imaging using second harmonic generation (SHG). The difficulty of label-free cardiac SHG imaging is that both collagen (i.e., collagen 1 fibrils) and myosin are ...
Jones, Bryce A., Torrado, Belen, Myakala, Komuraiah, Wang, Xiaoxin X., Perry, Priscilla E., Rosenberg, Avi Z., Levi, Moshe, Ranjit, Suman   +7 more
openaire   +2 more sources

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Preventive effect of Moringa oleifera seed oil (MOSEIL) in mice (Mus musculus) liver fibrosis model [PDF]

BIO Web of Conferences
Persistent liver injury leads to liver fibrosis, a pathological condition distinguished by the excessive deposition of extracellular matrix components, especially collagen.
Azizah Khulud Rizqi, Susanto Hendra, Lestari Sri Rahayu, Malek Nik Ahmad Nizam Nik   +3 more
doaj   +1 more source