Results 21 to 30 of about 3,539,899 (186)

Spatial Investigation of Facet Joint Cartilage Properties Reveals Specific Structure-Function Relationships. [PDF]

open access: yesJOR Spine
The inferior facet of the L2 vertebra and the superior facet of the L3 vertebra were harvested from ovine lumbar spines. The spatial biomechanical properties of the facet cartilage surfaces were determined by indentation mapping. Cartilage structure was spatially analyzed on a macroscopic and microscopic level.
de Roy L   +6 more
europepmc   +2 more sources

Determination of collagen content within picrosirius red stained paraffin-embedded tissue sections using fluorescence microscopy

open access: yesMethodsX, 2015
Picrosirius red (PSR) staining is a commonly used histological technique to visualize collagen in paraffin-embedded tissue sections. PSR stained collagen appears red in light microscopy.
Benjamin Vogel   +3 more
doaj   +2 more sources

Exacerbated expansive vascular remodeling due to disturbed flow in male mice overexpressing protein disulfide isomerase-A1. [PDF]

open access: yesPhysiol Rep
Abstract Vascular expansive remodeling is involved in atherosclerosis/restenosis; however, its mechanisms need further investigation. Protein‐disulfide isomerase (PDIA1), a redox chaperone from the endoplasmic reticulum and cell surface, supports vascular smooth muscle mechanoadaptation.
de Souza JMF   +5 more
europepmc   +2 more sources

Histomorphological evaluation of stromal collagen in canine mammary tumours: A study using picrosirius red stain and polarizing microscopy [PDF]

open access: yesJournal of Veterinary and Animal Sciences, 2023
Mammary gland tumours are considered as the most common neoplasms in sexually intact female dogs. Incidence of mammary tumours, especially the malignant ones are found to be rare in dogs younger than five years of age.
Keerthana Santhosh   +4 more
doaj   +1 more source

Picrosirius Red Stain

open access: yes, 2021
This data set contains picrosirius red ...
Rausch, Manuel
core   +1 more source

Collagenase treatment reduces the anisotropy of ultrasonic backscatter in rat myocardium by reducing collagen crosslinks

open access: yesPhysiological Reports, 2023
Dysregulation of collagen deposition, degradation, and crosslinking in the heart occur in response to increased physiological stress. Collagen content has been associated with ultrasonic backscatter (brightness), and we have shown that the anisotropy of ...
Lindsay A. Pittman   +3 more
doaj   +1 more source

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro   +17 more
wiley   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

open access: yesHepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog   +12 more
wiley   +1 more source

Postoperative pancreatic fistula affects recurrence-free survival of pancreatic cancer patients.

open access: yesPLoS ONE, 2021
PurposePostoperative pancreatic fistula (POPF) with reported incidence rates up to 45% contributes substantially to overall morbidity. In this study, we conducted a retrospective evaluation of POPF along with its potential perioperative clinical risk ...
Sameer A Dhayat   +6 more
doaj   +1 more source

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