Evaluation of dermal collagen stained with picrosirius red and examined under polarized light microscopy [PDF]
: The special picrosirius red staining highlights the natural birefringence of collagen fibers when exposed to polarized light. The results from birefringence allow to evaluate the organization of the collagen fibers in the tissues. The authors intend to
Polyana Galvão Bernardes Coelho +4 more
doaj +8 more sources
Digital Image Analysis of Picrosirius Red Staining: A Robust Method for Multi-Organ Fibrosis Quantification and Characterization [PDF]
Current understanding of fibrosis remains incomplete despite the increasing burden of related diseases. Preclinical models are used to dissect the pathogenesis and dynamics of fibrosis, and to evaluate anti-fibrotic therapies.
Guillaume E. Courtoy +7 more
doaj +11 more sources
Picrosirius Red and Polarization Microscopy – A Tool for Gender Differentiation [PDF]
Introduction: Forensic dentistry is a branch of dentistry which in collaboration with legal profession serves an important role to maintain justice system of a country. Forensic dentists play a major role in identification of an individual. Within the
BK Charan Gowda +3 more
doaj +4 more sources
Quantification and characterization of lung fibrosis in ARDS patients using picrosirius red staining [PDF]
IntroductionEvolution toward diffuse lung fibrosis is common in patients with ARDS but remains poorly characterized. In particular, the quantification and characterization of collagen fibers in lung tissue from patients with ARDS has not been performed ...
Ludovic Gerard +16 more
doaj +5 more sources
Fluorescence of Picrosirius Red Multiplexed With Immunohistochemistry for the Quantitative Assessment of Collagen in Tissue Sections [PDF]
The low cost and simplicity of picrosirius red (PSR) staining have driven its popularity for collagen detection in tissue sections. We extended the versatility of this method by using fluorescent imaging to detect the PSR signal and applying automated quantification tools. We also developed the first PSR protocol that is fully compatible with multiplex
Kyle A Wegner +2 more
exaly +5 more sources
Polarimetric imaging of collagen in histopathology specimens: an investigation of congo red and picrosirius red-stained placenta and skin [PDF]
Polarisation microscopy is a label-free technique whose tissue architecture profiling through anisotropy remains underinvestigated. In histology, bright-field microscopy and special stains remain the standard for investigating extracellular matrix (ECM ...
Georgia Mappa +8 more
doaj +3 more sources
Background: Collagen fibers are the main element of gingival connective tissue and contribute a leading role in the preservation of structural integrity and tissue function.
Anu Chandran +3 more
doaj +4 more sources
Background: Solid multicystic ameloblastoma (SMA) is a locally aggressive, benign odontogenic tumor of odontogenic origin with greater rate of recurrence.
Sanjay G Thete +5 more
doaj +2 more sources
Polarized Microscopic Analysis of Picrosirius Red Stained Salivary Gland Pathologies: An Observational Study. [PDF]
Abstract Objective Salivary gland diseases and their pathologies may affect the glandular structure including collagen, a major stromal component, in response to tissue damage or diseases. This study aimed to examine the changes in collagens in different salivary gland diseases using polarized picrosirius red staining. Materials and
Juengsomjit R +4 more
europepmc +3 more sources
Qualitative Analysis of Collagen Fibers in Oral Submucous Fibrosis using Picrosirius Red Stain and Polarising Microscope [PDF]
Introduction: Oral Submucous Fibrosis (OSMF) is an oral potentially malignant condition caused predominantly by areca nut chewing. Early recognition with accurate staging of the disease and appropriate treatment planning is of utmost importance to ...
T. Radhika +2 more
doaj +2 more sources

