Results 121 to 130 of about 258,140 (267)
Formation of the World Picture
European Journal of Technology and Design, 2020 openaire +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
A study of competitions in different fields through graphs under bipolar picture fuzzy environment. [PDF]
PLoS OneKhan WA +4 more
europepmc +1 more source
Space and time: Russian phraseological picture of the world vs scientific picture of the world
Theoretical and Applied Linguistics, 2020 Evgeniya V. Glazanova, Elena V. Erofeeva
openaire +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Diagnostic perspectives on mixed connective tissue disease with tuberculosis overlap. [PDF]
World J Clin CasesDhotre SV +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Formation of the core competencies of students: the poetic text in lingvoculturological aspect
Филологический класс, 2013 The fragment of work of formation of competence of process of perception of the poetic text is presented in article at literature lessons in the senior classes.
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Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Care for survivors when an emergency ends. [PDF]
Bull World Health OrganKamil A, Farooq AR.
europepmc +1 more source