Results 141 to 150 of about 86,123 (304)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Refuelling VH-UQP De Havilland plane by kerosene tin, Salamaua, New Guinea, 1933 [1] [picture] /

open access: yes, 1933
Part of the collection: Sarah Chinnery photographic collection of New Guinea, England and Australia.; Inscriptions: "At Salamaua" --In pencil on reverse. "Neg.
Chinnery, Sarah Johnston, 1887-1970.
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Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Dr Jean White's plane [picture] /

open access: yes, 1938
Title devised by cataloguer based on accompanying documentation.; Part of the Australian Inland Mission collection.; Attribution is uncertain.; Condition: Good.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla.pic ...
Flynn, John, 1880-1951.
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

United States army mechanicians surrounding The Southern Cross plane after landing at Honolulu, 1 June 1928 [picture].

open access: yes, 1928
Title devised by cataloguer based on accompanying documentation.; Part of: Tahiti to America, 14 July, 1927.; Inscriptions: "H. 7", "U.S. Army mechanicians surrounding plane as we approach crowd" and "B1"--In pencil on verso.; Condition: Fair.; Attached ...

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Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The choice of view point, picture plane and center of projection for visualization of the threedimensional stage

open access: yes, 2018
Рассмотрен выбор главных элементов построения перспективы. Приведены доказательства утверждений о том, что для построения перспективы, близкой зрительному восприятию, точка зрения должна находиться в главной точке картины, изображаемый предмет – в ...
Ницын, Александр Юрьевич
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EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

De Havilland plane VH-UQP beside a bullock wagon at Wau, New Guinea, 1933 [picture] /

open access: yes, 1933
Part of the collection: Sarah Chinnery photographic collection of New Guinea, England and Australia.; De Havilland plane, Wau 1933. "Ancient and modern transport", -- Accompanying notes from family.; Inscriptions: "Neg. no.
Chinnery, Sarah Johnston, 1887-1970.
core  

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