Dysflective cones: Visual function and cone reflectivity in long-term follow-up of acute bilateral foveolitis [PDF]
American Journal of Ophthalmology Case Reports, 2017 Purpose: Confocal adaptive optics scanning laser ophthalmoscope (AOSLO) images provide a sensitive measure of cone structure. However, the relationship between structural findings of diminished cone reflectivity and visual function is unclear.
Joanna H. Tu +9 more
doaj +3 more sources
The Cone-specific visual cycle [PDF]
Progress in Retinal and Eye Research, 2011 Cone photoreceptors mediate our daytime vision and function under bright and rapidly-changing light conditions. As their visual pigment is destroyed in the process of photoactivation, the continuous function of cones imposes the need for rapid recycling of their chromophore and regeneration of their pigment.
Jin-Shan, Wang, Vladimir J, Kefalov
openaire +4 more sources
Morphologic assessment of photoreceptors after idiopathic epiretinal membrane surgery with adaptive-optics SLO [PDF]
BMC OphthalmologyPurpose This study aims to quantitatively assess morphological alterations in cone cells following idiopathic epiretinal membrane (IERM) surgery using adaptive optics scanning light ophthalmoscopy (AO-SLO) and to correlate these findings with retinal ...
Pengfeng Li +7 more
doaj +2 more sources
Visual responses in mice lacking critical components of all known retinal phototransduction cascades. [PDF]
PLoS ONE, 2010 The mammalian visual system relies upon light detection by outer-retinal rod/cone photoreceptors and melanopsin-expressing retinal ganglion cells. Gnat1(-/-);Cnga3(-/-);Opn4(-/-) mice lack critical elements of each of these photoreceptive mechanisms via ...
Annette E Allen +4 more
doaj +2 more sources
Visual Cone Arrestin 4 Contributes to Visual Function and Cone Health. [PDF]
Invest Ophthalmol Vis Sci, 2015 Visual arrestins (ARR) play a critical role in shutoff of rod and cone phototransduction. When electrophysiological responses are measured for a single mouse cone photoreceptor, ARR1 expression can substitute for ARR4 in cone pigment desensitization; however, each arrestin may also contribute its own, unique role to modulate other cellular functions.A ...
Deming JD +9 more
europepmc +4 more sources
Physiological basis of resolution acuity in vision [PDF]
Nature CommunicationsVision is the primary sensory modality for many animals, especially humans and other primates. A fundamental constraint on visual resolution acuity is set by the size and spacing of cone photoreceptors, notably in the fovea of the retina where cones are ...
Keaton M. Ramsey +5 more
doaj +2 more sources
Ultrafast Transient Absorption Spectra and Kinetics of Rod and Cone Visual Pigments
Molecules, 2023 Rods and cones are the photoreceptor cells containing the visual pigment proteins that initiate visual phototransduction following the absorption of a photon.
Arjun Krishnamoorthi +3 more
doaj +1 more source
Enhanced S-Cone Syndrome: Elevated Cone Counts Confer Supernormal Visual Acuity in the S-Cone Pathway [PDF]
Investigative Opthalmology & Visual Science, 2023 To measure photoreceptor packing density and S-cone spatial resolution as a function of retinal eccentricity in patients with enhanced S-cone syndrome (ESCS) and to discuss the possible mechanisms supporting their supernormal S-cone acuity.We used an adaptive optics scanning laser ophthalmoscope (AOSLO) to characterize photoreceptor packing.
Wang, Yiyi +4 more
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Childhood-onset genetic cone-rod photoreceptor diseases and underlying pathobiology
EBioMedicine, 2021 Inherited retinal diseases (IRDs) were first classified clinically by history, ophthalmoscopic appearance, type of visual field defects, and electroretinography (ERG).
Alexandra V. Garafalo +5 more
doaj +1 more source
Objective assessment of foveal cone loss ratio in surgically closed macular holes using adaptive optics scanning laser ophthalmoscopy. [PDF]
PLoS ONE, 2013 PURPOSE: To use adaptive optics scanning laser ophthalmoscopy (AO-SLO) to quantify cone loss ratio in the foveola in order to assess foveal cone status and to investigate relationships between foveal structural abnormalities and visual function in ...
Satoshi Yokota +7 more
doaj +1 more source