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Lrit1, a Retinal Transmembrane Protein, Regulates Selective Synapse Formation in Cone Photoreceptor Cells and Visual Acuity

open access: yesCell Reports, 2018
Summary: In the vertebrate retina, cone photoreceptors play crucial roles in photopic vision by transmitting light-evoked signals to ON- and/or OFF-bipolar cells.
Akiko Ueno   +12 more
doaj   +4 more sources

Visual Cone Arrestin 4 Contributes to Visual Function and Cone Health [PDF]

open access: yesInvestigative Opthalmology & Visual Science, 2015
Visual arrestins (ARR) play a critical role in shutoff of rod and cone phototransduction. When electrophysiological responses are measured for a single mouse cone photoreceptor, ARR1 expression can substitute for ARR4 in cone pigment desensitization; however, each arrestin may also contribute its own, unique role to modulate other cellular functions.A ...
Janise D, Deming   +9 more
openaire   +3 more sources

The Cone-specific visual cycle [PDF]

open access: yesProgress in Retinal and Eye Research, 2011
Cone photoreceptors mediate our daytime vision and function under bright and rapidly-changing light conditions. As their visual pigment is destroyed in the process of photoactivation, the continuous function of cones imposes the need for rapid recycling of their chromophore and regeneration of their pigment.
Vladimir J Kefalov
exaly   +3 more sources

A novel cone visual cycle in the cone-dominated retina [PDF]

open access: yesExperimental Eye Research, 2007
The visual processing of humans is primarily reliant upon the sensitivity of cone photoreceptors to light during daylight conditions. This underscores the importance of understanding how cone photoreceptors maintain the ability to detect light. The vertebrate retina consists of a combination of both rod and cone photoreceptors.
Donald M Allen, Andrew T C Tsin
exaly   +3 more sources

Morphologic assessment of photoreceptors after idiopathic epiretinal membrane surgery with adaptive-optics SLO [PDF]

open access: yesBMC Ophthalmology
Purpose This study aims to quantitatively assess morphological alterations in cone cells following idiopathic epiretinal membrane (IERM) surgery using adaptive optics scanning light ophthalmoscopy (AO-SLO) and to correlate these findings with retinal ...
Pengfeng Li   +7 more
doaj   +2 more sources

Physiological basis of resolution acuity in vision [PDF]

open access: yesNature Communications
Vision is the primary sensory modality for many animals, especially humans and other primates. A fundamental constraint on visual resolution acuity is set by the size and spacing of cone photoreceptors, notably in theĀ fovea of the retina where cones are ...
Keaton M. Ramsey   +5 more
doaj   +2 more sources

Ultrafast Transient Absorption Spectra and Kinetics of Rod and Cone Visual Pigments

open access: yesMolecules, 2023
Rods and cones are the photoreceptor cells containing the visual pigment proteins that initiate visual phototransduction following the absorption of a photon.
Arjun Krishnamoorthi   +3 more
doaj   +1 more source

Childhood-onset genetic cone-rod photoreceptor diseases and underlying pathobiology

open access: yesEBioMedicine, 2021
Inherited retinal diseases (IRDs) were first classified clinically by history, ophthalmoscopic appearance, type of visual field defects, and electroretinography (ERG).
Alexandra V. Garafalo   +5 more
doaj   +1 more source

Objective assessment of foveal cone loss ratio in surgically closed macular holes using adaptive optics scanning laser ophthalmoscopy. [PDF]

open access: yesPLoS ONE, 2013
PURPOSE: To use adaptive optics scanning laser ophthalmoscopy (AO-SLO) to quantify cone loss ratio in the foveola in order to assess foveal cone status and to investigate relationships between foveal structural abnormalities and visual function in ...
Satoshi Yokota   +7 more
doaj   +1 more source

Seeing invisible light: 2-photon microperimetry to measure visual function

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: The accuracy of conventional visual function tests, which emit visible light, decreases in patients with corneal scars, cataracts, and vitreous hemorrhages.
Urmi Mehta   +3 more
doaj   +1 more source

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