Results 41 to 50 of about 72,833 (298)

The integration of local chromatic motion signals is sensitive to contrast polarity [PDF]

, 2011
Peer ...
Martinovic, Jasna, Malek, Stephanie, Ruppertsberg, Alexa, MARCO BERTAMINI, JASNA MARTINOVIC, SOPHIE M. WUERGER, STEPHANIE MALEK, Bertamini, Marco, Wuerger, Sophie M., ALEXA RUPPERTSBERG   +9 more
core   +1 more source

Functional evidence for cone-specific connectivity in the human retina

, 2009
NoPhysiological studies of colour vision have not yet resolved the controversial issue of how chromatic opponency is constructed at a neuronal level. Two competing theories, the cone-selective hypothesis and the random-wiring hypothesis, are currently ...
McGraw, Paul V., McKeefry, Declan J., Whitaker, David J., Vakrou, Chara   +3 more
core   +1 more source

Clinical Course, Genetic Etiology, and Visual Outcome in Cone and Cone–Rod Dystrophy

Ophthalmology, 2012
To evaluate the clinical course, genetic etiology, and visual prognosis in patients with cone dystrophy (CD) and cone-rod dystrophy (CRD).Clinic-based, longitudinal, multicenter study.Consecutive probands with CD (N = 98), CRD (N = 83), and affected relatives (N = 41 and N = 17, respectively) from various ophthalmogenetic clinics in The Netherlands ...
Thiadens, A.A., Phan, T.M., Zekveld-Vroon, R.C., Leroy, B.P., van den Born, L.I., Hoyng, C.B., Klaver, C.C., Writing Committee for the Cone Disorders Study Group, C., Roosing, S., Roosing, S., Pott, J.W., van Schooneveld, M.J., van Moll-Ramirez, N., van Genderen, M.M., Boon, C.J.F., den Hollander, A.I., den Hollander, A.I., Bergen, A.A., De Baere, E., Cremers, F.P., Lotery, A.J.   +20 more
openaire   +6 more sources

Effect of rod-cone interactions on mesopic visual performance mediated by chromatic and luminance pathways

, 2014
We studied the effect of rod-cone interactions on mesopic visual reaction time (RT). Rod and cone photoreceptor excitations were independently controlled using a four-primary photostimulator.
Cao, Dingcai, Zele, Andrew J., Maynard, Michelle L., Joyce, Daniel S.   +3 more
core   +1 more source

Loss of Foveal Cone Structure Precedes Loss of Visual Acuity in Patients With Rod-Cone Degeneration [PDF]

, 2019
Purpose: To assess the relationship between cone spacing and visual acuity in eyes with rod-cone degeneration (RCD) followed longitudinally. Methods: High-resolution images of the retina were obtained using adaptive optics scanning laser ophthalmoscopy ...
Griffin, Shane, Bensinger, Ethan, Loumou, Panagiota, Qin, Jia, Roorda, Austin, Saud, Asma, Duncan, Jacque L, Rinella, Nicholas, Porco, Travis C, Ratnam, Kavitha   +9 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Colour and melanopsin mediated responses in the murine retina

Frontiers in Cellular Neuroscience, 2023
Introduction: Intrinsically photosensitive retinal ganglion cells (ipRGCs) integrate melanopsin and rod/cone-mediated inputs to signal to the brain. Whilst originally identified as a cell type specialised for encoding ambient illumination, several lines ...
Joshua W. Mouland, Joshua W. Mouland, Alex J. Watson, Alex J. Watson, Franck P. Martial, Franck P. Martial, Robert J. Lucas, Robert J. Lucas, Timothy M. Brown, Timothy M. Brown   +9 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Wiring a periscope--ocelli, retinula axons, visual neuropils and the ancestrality of sea spiders. [PDF]

, 2012
The Pycnogonida or sea spiders are cryptic, eight-legged arthropods with four median ocelli in a 'periscope' or eye tubercle. In older attempts at reconstructing phylogeny they were Arthropoda incertae sedis, but recent molecular trees placed them as the
Roland R Melzer, Hess, Martin, Martin Hess, Lehmann, Tobias, Melzer Roland R., Lehmann Tobias, Tobias Lehmann, Melzer, Roland R., Heß Martin   +8 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source