Results 181 to 190 of about 1,689,649 (265)

Portrait of the Venerable Archdeacon Cowper, D.D. [picture].

Plate on p. 52 of: Australian picture pleasure book /Walter G.
Mason, Walter G.
core  

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Melting Temperature Under Pressure in 'Hard' and Soft Matter. [PDF]

Int J Mol Sci
Drozd-Rzoska A, Rzoska SJ, Grzegory I, Porowski S.   +3 more
europepmc   +1 more source

Mr G.V. Brooke as King Lear [picture].

Plate on p. 58 of: Australian picture pleasure book /Walter G.
Mason, Walter G.
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Multidimensional spectro-temporal imaging of exciton dynamics under propagating acoustic strain in two-dimensional semiconductors. [PDF]

Sci Adv
Takahashi Y, Yamamoto T, Kanzawa H, Maezawa K, Kumazaki H, Kato YK, Watanabe S, Fujii S.   +7 more
europepmc   +1 more source

Raymond Terrace, Hunter River, New South Wales [picture].

Plate on p. 33 of: Australian picture pleasure book /Walter G.
Mason, Walter G.
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Global current systems in the magnetosphere of Mercury. [PDF]

Nat Commun
Lin R, Huang S, Yuan Z, Slavin JA, Sahraoui F, Raines JM, Jiang K, Chai L, Wu H, Dong Y, Anderson BJ, Wei Y, Xu S, Xiong Q, Zhang J, Wang Z, Yu L.   +16 more
europepmc   +1 more source

The Lawrence Rocks, near Portland Bay, South Australia [picture].

Plate on p. 50 of: Australian picture pleasure book /Watler G.
Mason, Walter G.
core