Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Closed-Loop Optogenetic Control in a Microplate Reader. [PDF]
ACS Synth BiolNamboothiri HR +4 more
europepmc +1 more source
Digital Professional Practice, Digital Competences and Impact on Family Support Services
Child &Family Social Work, EarlyView.ABSTRACT Digital‐mediated practices in public social services require new strategies for administration, communication, assessment and intervention. Within this field, research framed under UNESCO's (2020) Media and Information Literacy model—examining digital media management and digital competence in information management, communication, digital ...
Guacimara Rodríguez +6 more
wiley +1 more source
A Novel Algebraic Saturation-Based PID Controller Optimized by Animated Oat Algorithm for Ultra-Fast Dynamic Response of Automatic Voltage Regulation. [PDF]
Biomimetics (Basel)Türksoy Ö.
europepmc +1 more source
Child &Family Social Work, EarlyView.ABSTRACT This study examined the efficacy of a 5‐week combined psychoeducation and support programme aimed at enhancing emotional competencies and psychological well‐being among Spanish auxiliary grandparent caregivers. Two delivery formats (face‐to‐face and synchronous online) were compared with a control group receiving no intervention, and ...
Cristina Noriega +4 more
wiley +1 more source
Robust performance optimization of UAV dynamic systems using MPC-PID hybrid control. [PDF]
Sci RepZhou W, Zhou L, Yuan T, Chen R, Liu D.
europepmc +1 more source
Defining the role of αC helix interactions in the activation of the integrin αI domain
The FEBS Journal, EarlyView.The α2I domain of the α2β1 integrin contains a distinctive αC helix and a conserved Arg288‐Glu318 ion pair that stabilizes the closed state of the domain. Disruption of this ion pair in the activated α2I variant unwinds the αC helix, which allows interaction with additional collagen‐binding sites increasing collagen binding.
Liisa Pösö +7 more
wiley +1 more source
Stability control of suspended monorail vehicles based on PID and quadratic programming allocation. [PDF]
Sci RepJiang Y, Wang D, Chen R, Wang Q, Du Z.
europepmc +1 more source
When to consider an inborn error of immunity: clues for physicians
Internal Medicine Journal, EarlyView.Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley +1 more source
Adaptability Study of Pressure Regulators in Hydrogen-Blended Natural Gas Pipelines. [PDF]
ACS OmegaXue Y, Li X, Liu Y, Yuan J, Hua J, Wu Y.
europepmc +1 more source