Results 41 to 50 of about 1,464,600 (373)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A prophylaxis algorithm for deep vein thrombosis in ankle and foot surgery

Revista de la Asociación Argentina de Ortopedia y Traumatología, 2019
Introduction: Deep vein thrombosis (DVT) is a major complication in orthopedic surgery. According to the literature, thromboprophylaxis in foot and ankle surgery is not a standardized practice due to the low incidence of DVT.
Héctor Masaragian, Fernando Perin, Hernán Coria, Luciano Mizdraji, Nicolás Ameriso, Leonel Rega   +5 more
doaj   +1 more source

Técnica de Masquelet para defecto óseo en quinto metatarsiano. Reporte de caso clínico

Revista Colombiana de Ortopedia y Traumatología, 2021
Introducción: la técnica de masquelet se utiliza en el tratamiento de los defectos óseos de los huesos largos con éxito. En el pie se ha descrito para el tratamiento de perdidas oseas en el 1er metatarsiano y medio pie.
Fabián Alberto Romero-Berrío, Julián Andrés Castellanos-Jiménez, Edgar Hernández-Perdomo   +2 more
doaj   +1 more source

Point Information Gain and Multidimensional Data Analysis

, 2016
We generalize the Point information gain (PIG) and derived quantities, i.e. Point information entropy (PIE) and Point information entropy density (PIED), for the case of R\'enyi entropy and simulate the behavior of PIG for typical distributions.
Císař, Petr, Korbel, Jan, Macháček, Petr, Rychtáriková, Renata, Soloviov, Dmytro, Urban, Jan, Štys, Dalibor   +6 more
core   +2 more sources

Magnetic resonance imaging: a tool for pork pie development [PDF]

, 2013
The traditional British pork pie consists of roughly chopped pork cooked in a hot water pastry crust. Due to shrinkage of the meat during cooking, the gap formed around the meat is usually sealed using a gelatin based jelly to exclude air and thus help ...
Gaunt, AP, Morris, RH, Newton, MI
core   +3 more sources

Does the Circular Economy Grow the Pie? The Case of Rebound Effects From Smartphone Reuse

Frontiers in Energy Research, 2018
The environmental benefits of the circular economy (CE) are often taken for granted. There are, however, reasons to believe that rebound effects may counteract such benefits by increasing overall consumption or ‘growing the pie’.
Tamar Makov, David Font Vivanco
semanticscholar   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Pemanfaatan Pati Garut pada Pembuatan Produk Cookies sebagai Upaya Peningkatan Bahan Pangan Lokal”(Erut Cheese Pie Cookies, Erut Ginger Nut Cookies, dan Erut Peanut Honey Cookies)” [PDF]

, 2012
Penelitian ini bertujuan untuk : 1) Menemukan formula produk Erut cheese pie cookies, Erut ginger nut cookies dan Erut peanut honey cookies yang tepat, 2) Mengembangkan teknik olah produk Erut chesse pie cookies, Erut ginger nut cookies dan Erut peanut ...
TANJUNG AJI NUR , MUSTOFA
core  

Easy as (Happiness) Pie? A Critical Evaluation of a Popular Model of the Determinants of Well-Being

Journal of Happiness Studies, 2019
An underlying principle behind much of the research in positive psychology is that individuals have considerable leeway to increase their levels of happiness. In an influential article that is frequently cited in support of such claims, Lyubomirsky et al.
Nicholas J. L. Brown, J. Rohrer
semanticscholar   +1 more source

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source