Results 71 to 80 of about 1,392,738 (297)

Identification, Control, and Characterization of Peristaltic Pumps in Hemodialysis Machines

open access: yesApplied System Innovation
Peristaltic pumps represent a fundamental component of hemodialysis machines. They facilitate the transfer of fluids, particularly in the collection and treatment of blood.
Cristian H. Sánchez-Saquín   +4 more
doaj   +1 more source

RETREG1‐Mediated Reticulophagy is Essential for Dendritic Cell Maturation and Function in Sepsis

open access: yesAdvanced Science, EarlyView.
Reticulophagy regulator 1 (RETREG1) maintains dendritic cell (DC) maturation and function in early sepsis. Mechanistically, activating transcription factor 6 (ATF6) acts as a direct transcription factor regulating RETREG1 expression in response to sepsis‐induced endoplasmic reticulum (ER) stress.
Ren‐Qi Yao   +28 more
wiley   +1 more source

Comments on Allan Bomhard, “The Origins of Proto-Indo-European: The Caucasian substrate hypothesis” [PDF]

open access: yes, 2019
The main claims of Bomhard's paper are that PIE originated in Central Asia, which accounts for its Eurasiatic properties such as resemblant pronouns (Uralic, IE, Kartvelian, Turkic, Mongolic, Tungusic) and originally agglutinating morphology; then it ...
Nichols, J
core  

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

open access: yesAdvanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao   +16 more
wiley   +1 more source

Integrated Single‐Cell and Spatial Transcriptomics Reveal Cell‐Type‐Specific Immune Regulatory Networks in Maize Responding to Southern Corn Rust

open access: yesAdvanced Science, EarlyView.
By integrating single‐nuclei and spatial transcriptomics, this study presents a stereoscopic landscape of maize leaf to Puccinia polysora infection. Epidermal and mesophyll cells initiate primary defenses via RLPs/RLKs and jasmonic acid signaling. Cell‐cell communication analyses further reveal the underlying the dynamics of the underlying immune ...
Qiongqiong Wang   +16 more
wiley   +1 more source

Metrología y modulación en las mezquitas: propuesta de análisis a través de cuatro casos cordobeses

open access: yesArqueología de la Arquitectura, 2017
En este artículo proponemos un acercamiento a la estructura y diseño arquitectónico de las mezquitas cordobesas mediante el análisis metrológico y de modulación de algunos conjuntos excavados en la capital andalusí.
Carmen González Gutiérrez
doaj   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

open access: yesAdvanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang   +16 more
wiley   +1 more source

Luxación tibio-peronea superior

open access: yesCirugía del Uruguay, 2020
Presentado a la Sesión del 8 de Octubre de 1941.
Eugenio Prat   +2 more
doaj  

The Official Student Newspaper of UAS [PDF]

open access: yes, 2016
Letter from the Editor / Whalesong Staff -- UAS In Brief -- Health Corner / Helping with Anxiety -- UAS Social Media -- Gender Inclusive Housing -- REC Center Gear Review -- Invasive Species / Apple Pie Bites -- Linked In / Walkabout -- Beer and the ...

core  

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

open access: yesAdvanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia   +5 more
wiley   +1 more source

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