Results 91 to 100 of about 195,293 (306)
Single-stage management of Charcot neuroarthropathy and osteomyelitis in diabetic patients
Journal of the Foot & AnkleObjective: Describe our experience treating Charcot neuroarthropathy (CN) coexisting with concurrent bone infection in a single step, treated with external fixation, and report the mid-term radiographic and functional outcomes.
gonzalo alvarez +4 more
doaj +1 more source
Advanced Science, EarlyView.The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao +8 more
wiley +1 more source
Advanced Science, EarlyView.We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du +11 more
wiley +1 more source
Identification, Control, and Characterization of Peristaltic Pumps in Hemodialysis Machines
Applied System InnovationPeristaltic pumps represent a fundamental component of hemodialysis machines. They facilitate the transfer of fluids, particularly in the collection and treatment of blood.
Cristian H. Sánchez-Saquín +4 more
doaj +1 more source
Science, 2014 When I am asked how I became a developmental biologist, I say, “Jim hired me for my rhubarb pie and my Phi Beta Kappa key, and the rest is history.” I did not set out to become a scientist. I majored in history as an undergraduate—at Pomona College in Claremont, California, class of 1963—then bailed on graduate school and became an elementary school ...
openaire +2 more sources
Extra Climate Benefits From Afforestation Due to Reduced Forest Fragmentation in China
Advanced Science, EarlyView.Afforestation in China reduced forest fragmentation in 2015, transforming 51.8 M ha of edge forests into interior forests. This enhanced carbon sequestration (1.4±0.2 Pg CO2e, a cooling biogeochemical effect), while reduced albedo (−0.9 Pg CO2e, a warming biophysical effect) partially offset the gain, yielding a net extra climate benefit of ...
Nan Meng +19 more
wiley +1 more source
Festum paschatis pie celebrandum civibus academicis indicunt prorector, cancellarius, director et senatus Academiae Albertinae [PDF]
1826: Festos Jesu Christi redivivi dies pie celebrandos indicunt Academiae Albertinae prorector, cancellarius, director et senatus1828; 1830: Jesu Christi in vitam reducis memoriam festis diebus pie recolendam indicunt Academiae Albertinae prorector ...
Albertus-Universität zu Königsberg i. Pr.
core +1 more source
The Spatiotemporal Genetic Architecture of Seed Vigor in Upland Cotton
Advanced Science, EarlyView.Leveraging the semi‐automated SeedRanger platform, we profiled the germination kinetics of 356 cotton accessions at a 30‐min interval. This high‐throughput phenomic approach delineated a temporal genetic network comprising 541 stage‐specific loci. Crucially, functional validation identified FLA2 as a pivotal, auxin‐modulated regulator that orchestrates
Luyao Wang +32 more
wiley +1 more source