Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto +11 more
wiley +1 more source
Comprehensive genome analysis uncovers the diversity of jumbo phages in the pig gut microbiome. [PDF]
Wei C, Chen Z.
europepmc +1 more source
Effects of intravitreal ropivacaine on retinal thickness and integrity in the guinea pig
Gönül Ölmez Kavak +4 more
openalex +2 more sources
Evaluation of Solid-Phase Chemiluminescent Enzyme Immunoassay, Enzyme-Linked Immunosorbent Assay, and Latex Agglutination Tests for Screening Toxoplasma IgG in Samples Obtained from Cats and Pigs [PDF]
Ashok K. Singh
openalex +1 more source
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang +27 more
wiley +1 more source
Podocyte infolding glomerulopathy in a Japanese girl with systemic lupus erythematosus. [PDF]
Watanabe S +4 more
europepmc +1 more source
In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du +6 more
wiley +1 more source
One health approach to Balantioides coli: Molecular and metabarcoding evidence of zoonotic transmission. [PDF]
Class CSC +9 more
europepmc +1 more source
EXUDATIVE EPIDERMITIS OF PIGS: FEATURES OF ETIOLOGY AND MANIFESTATION
A.I. Laishevtcev +5 more
openalex +1 more source

