Results 191 to 200 of about 1,220,264 (340)

Engineered GM1 Intersects Between Mitochondrial and Synaptic Pathways to Ameliorate ALS Pathology

open access: yesAdvanced Science, EarlyView.
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease driven by genetic and molecular disruptions affecting energy balance, protein homeostasis, and stress responses in nerve cells. Studies using human and rodent models identified convergent defects in mitochondria and synaptic function.
Federica Pilotto   +11 more
wiley   +1 more source

Effects of intravitreal ropivacaine on retinal thickness and integrity in the guinea pig

open access: green, 2005
Gönül Ölmez Kavak   +4 more
openalex   +2 more sources

The Evolutionarily Conserved TPM1 Super‐Enhancer Drives Skeletal Muscle Regeneration via Mechanotransduction Signaling

open access: yesAdvanced Science, EarlyView.
By integrating biomechanical and epigenetic cues, the evolutionarily conserved TPM1 super‐enhancer drives myogenesis via TEAD4‐mediated chromatin looping. This mechanism produces species‐specific outputs (linear TPM1 mRNA in mice and CircTPM1 in bovine) that activate PI3K/AKT mechanotransduction and the MYH10/MYL3 axis to execute cytoskeletal ...
Ruimen Zhang   +27 more
wiley   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

open access: yesAdvanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du   +6 more
wiley   +1 more source

One health approach to Balantioides coli: Molecular and metabarcoding evidence of zoonotic transmission. [PDF]

open access: yesPLoS One
Class CSC   +9 more
europepmc   +1 more source

EXUDATIVE EPIDERMITIS OF PIGS: FEATURES OF ETIOLOGY AND MANIFESTATION

open access: gold, 2017
A.I. Laishevtcev   +5 more
openalex   +1 more source

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