Results 171 to 180 of about 47,476 (262)

A Self-Amplifying RNA Lipid Nanoparticle (saRNA-LNP) Vaccine Provides Effective Protection Against Porcine Epidemic Diarrhea. [PDF]

Transbound Emerg Dis
Shu J, Zhang H, Wang F, Zhang H, Liu X, Liu K, Zha Y, Chai W, Yao J, Lin Y, Wu C, Zhao X.   +11 more
europepmc   +1 more source

Strategies for inducing diabetes in laboratory animals: Advances from chemical, surgical, immunologic, dietary, and genetic approaches

Animal Models and Experimental Medicine, EarlyView.
This review summarizes the principal experimental approaches used to induce diabetes in animal models. Strategies include chemical agents (streptozotocin, alloxan, dithizone, gold thioglucose), dietary interventions (high‐fat and high‐sugar diets), surgical methods (total or partial pancreatectomy), genetic models (db/db, ob/ob, Goto‐Kakizaki [GK ...
Milad Faraji, Maedeh Faraji, Nasrin Kazemipour   +2 more
wiley   +1 more source

Colonization Dynamics of <i>Clostridioides difficile</i> in Suckling and Weaning Piglets. [PDF]

Vet Sci
Martín Bermúdez A, Salido E, Ramos-Real MJ, Hernández-Sánchez C, Lecuona M, Arias A, González JC, Beamonte C, Hernández-Porto M.   +8 more
europepmc   +1 more source

Effects of post-farrowing feed delivery schedule and sow parity on piglet performance and survivability¹. [PDF]

Transl Anim Sci
Bardales-Castellanos AS, Bolivar-Sierra AF, Frobose H, Bradley C, Levesque CL.   +4 more
europepmc   +1 more source

Proinflammatory Epstein–Barr Virus Antibody Functions Track with Disease Activity in Multiple Sclerosis

Annals of Neurology, EarlyView.
Objective Epstein–Barr virus (EBV) has been implicated in the pathogenesis of multiple sclerosis (MS). Elevated immunoglobulin G (IgG) titers against EBV nuclear antigen 1 (EBNA1) represent the most consistent serological marker of MS risk, with levels remaining persistently elevated following disease onset.
Malina Behrens, Paula Terroba‐Navajas, Eline A.J. Willemse, Sabine Schädelin, Manuel Comabella, Christian Münz, Gordan Lauc, Yannic Bartsch, Jens Kuhle, Jan D. Lünemann   +9 more
wiley   +1 more source

Generalizable Strategies for the Synthesis of Cereblon‐Recruiting PROTAC Prodrugs

Angewandte Chemie, EarlyView.
Cereblon‐recruiting PROTACs remain challenging to derivatize for prodrug‐based delivery. In this study, three complementary conjugation strategies enabled the efficient synthesis of cleavable PROTAC prodrugs with tunable release kinetics that can be incorporated into a library of PEGylated constructs and bottlebrush prodrugs.
Aiden X. Wang, Bin Liu, Elise M. Ackerman, Yichen Xiang, Hung V.‐T. Nguyen, Yivan Jiang, Angela N. Koehler, Jeremiah A. Johnson   +7 more
wiley   +2 more sources

The Effect of Pellet Diameter on the Growth Performance, Nutrient Digestibility, and Intestinal Health of Piglets During the Creep Feeding Stage. [PDF]

Animals (Basel)
Kong L, Ou F, Dong S, Zhang N, Ma Y.
europepmc   +1 more source

Modeling Catheter‐Associated Bladder Mucosal Adhesion and Microtrauma Using a Human Urothelial Microtissue Model

Advanced NanoBiomed Research, EarlyView.
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley   +1 more source

Effects of Fermented Pea-Wheat Ingredient Inclusion in Soybean Meal-Replacement Diets on Intestinal Adaptation, Gut Microbiota, and Fecal Consistency in Weaned Piglets. [PDF]

Animals (Basel)
Alpár B, Varga L, Váradi A, Kaszab E, Somogyi Z, Tóth T.   +5 more
europepmc   +1 more source