Results 41 to 50 of about 47,476 (262)

Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan, Jordan Safran, Anna Loughman, Grace Lin, Shivanshi Vaid, Dana Allababidi, Peter M. Tessier, Louis T. Dang   +7 more
wiley   +1 more source

Dietary supplementation with Bacillus subtilis PB6 alleviates diarrhea and improves growth performance and immune function in weaned piglets fed a high-protein diet

Frontiers in Veterinary Science
This study aimed to evaluate the effects of dietary supplementation with Bacillus subtilis PB6 on growth performance, diarrhea scores, nutrient digestibility, immune function, and gut microbiota in weaned piglets fed a high-protein diet.
Yang Liu, Lei Cao, Chenhao Yu, Qiang Zhou, Hua Li, Ruinan Zhang, Jiayong Tang, Zhiming Zhang, Zheng Luo, Xuemei Jiang, Zhengfeng Fang, Yan Lin, Shengyu Xu, Yong Zhuo, Lun Hua, De Wu, Bin Feng, Lianqiang Che   +17 more
doaj   +1 more source

Comparisons of blood biochemical parameters, digestive enzyme activities and volatile fatty acid profile between Meishan and Yorkshire piglets

Animal Nutrition, 2015
This study was conducted to compare physiological characteristics between Meishan and Yorkshire piglets in their early lives. Six healthy purebred Meishan sows and Yorkshire sows with close farrowing dates were used in this research.
Shouqing Ma, Meilei Ma, Chunlong Mu, Kaifan Yu, Weiyun Zhu   +4 more
doaj   +1 more source

Comparison of Oropharyngeal Microbiota in Healthy Piglets and Piglets With Respiratory Disease

Frontiers in Microbiology, 2018
Porcine respiratory disease (PRD) is responsible for severe economic losses in the swine industry worldwide. Our objective was to characterize the oropharyngeal microbiota of suckling piglets and compare the microbiota of healthy piglets and piglets with PRD.
Qun Wang, Rujian Cai, Anni Huang, Xiaoru Wang, Wan Qu, Lei Shi, Lei Shi, Chunling Li, He Yan   +8 more
openaire   +3 more sources

Advances in Sustainable and Wearable Textile Based Soft Robotics

Advanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas, Marzia Dulal, Sophia K. Novoselov, Victoria K. Novoselov, Kostya S. Novoselov, Shaila Afroj, Nazmul Karim   +6 more
wiley   +1 more source

Effect of dietary tall oil fatty acids and hydrolysed yeast in SNP2-positive and SNP2-negative piglets challenged with F4 enterotoxigenic Escherichia coli

Scientific Reports
Reduction of post-weaning diarrhoea caused by ETEC is a principal objective in pig farming in terms of welfare benefits. This study determined the effects of genetic susceptibility and dietary strategies targeting inflammation and fimbriae adherence on ...
Anouschka Middelkoop, Hannele Kettunen, Xiaonan Guan, Juhani Vuorenmaa, Ramon Tichelaar, Michela Gambino, Martin Peter Rydal, Francesc Molist   +7 more
doaj   +1 more source

Effect of Housing of Lactating Sows on Their Reproductive Performance and Losses of Piglets From Birth to Weaning

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
The objective of this study was to evaluate selected reproductive parametres of sows stabled in farrowing houses with different technologies and losses of piglets from birth to weaning.
Pavel Nevrkla, Zdeněk Hadaš
doaj   +1 more source

The dna vaccine combining the adjuvant porcine il-12 with the spike gene of transmissible gastroenteritis virus enhances the immune response in swine [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2018
Transmissible gastroenteritis (TGE), cause by transmissible gastroenteritis virus (TGEV), is an acute digestive and highly infectious disease in piglets. In this study, porcine interleukin-12 immunological adjuvant combined with a DNA vaccine bearing the
Xunliang LI, Pengchong LI, Huijie CHEN, Fandan MENG, Xiaofeng REN, Guangxing LI   +5 more
doaj   +1 more source

Sodium Alginate‐Based Submucosal Lifting Hydrogel for Endoscopic Mucosal Resection and Endoscopic Submucosal Dissection

Advanced Healthcare Materials, EarlyView.
A biocompatible sodium alginate‐based hydrogel is developed as a next‐generation submucosal lifting agent intended for EMR and ESD. The optimized formulation exhibits a composition devoid of endotoxins, high viscosity, demonstrates reliable injectability, and ensures prolonged mucosal elevation.
Iram Maqsood, Venkata S. Akshintala, Surya T. Evani, Rebecca A. Krimins, Yihan Wang, Keith Freel, Ahmed Ibrahim, Saowanee Ngamruengphong, Mouen Khashab, Stephen W. Hoag   +9 more
wiley   +1 more source

Implication of Dietary Acidifiers for Growth Performance and Intestinal Morphometry in Nursery Piglets [PDF]

Brazilian Archives of Biology and Technology
This study was conducted to assess the use of dietary acidifiers and their effects on the growth performance and intestinal morphometry of challenged and non-challenged nursery piglets.
João Otávio Hilgemberg, Rafaela Hilgemberg, Guilherme Beber Jasluk, Cheila Roberta Lehnen   +3 more
doaj   +1 more source