Results 201 to 210 of about 5,150,325 (304)

Engineering Biology Beyond Single Genes: Advances and Challenges in Multiplex Genome Editing

Animal Research and One Health, EarlyView.
Multiplex genome editing is transforming genome engineering from single‐gene perturbation to network‐level control, yet its broader application remains limited by challenges in gRNA array engineering, delivery technologies, and safety management. Emerging AI‐driven approaches are accelerating guide RNA design and CRISPR effector optimization for ...
Linli Wang, Yongbin Liu, Hongbing Han
wiley   +1 more source

Cutaneous Pseudoepitheliomatous Hyperplasia Secondary to Embedded Canine Pet Hair Mimicking Squamous Cell Carcinoma. [PDF]

Case Rep Dermatol Med
Moore SG, Field MJ, D'Souza LS.
europepmc   +1 more source

Investigating Pompeii Subsoil Using Geomatics and Geophysics Merged Analyses

Archaeological Prospection, EarlyView.
ABSTRACT The archaeological site of Pompeii represents an exceptional context for the application of non‐invasive and integrated investigation methods aimed at enhancing the understanding of both exposed and buried remains. This study presents the results of multidisciplinary research conducted in the Palestra Grande site, a large and strategically ...
Valentina Santoro, Antonio Merico, Vincenzo Sapia, Gianluca Catanzariti, Valerio Materni, Giacomo Patrucco, Riccardo Olivito, Anna Anguissola, Ilaria Cangiano, Antonia Spanò   +9 more
wiley   +1 more source

Carotenoid-Rich Pigment Extract From Micrococcus terreus SK34 Induces Apoptosis in SH-SY5Y Neuroblastoma Cells: Integrated Metabolomic, Molecular Docking, and Experimental Validation. [PDF]

Microbiologyopen
Karaagac SI, Albayrak S, ShadiDizaji A, Kiziler ME, Eroglu E, Arslan NP, Taskin M.   +6 more
europepmc   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

S-nitrosylation topology in melanoma: established mechanisms, unresolved redox-immune links, and a testable framework. [PDF]

Redox Biol
Srivastava J, Premi S.
europepmc   +1 more source

Investigating the changes in skin color representation within US medical textbook imagery

Anatomical Sciences Education, EarlyView.
Abstract Medical education traditionally relies on textbooks with limited representation of dark skin tones, contributing to “visual racism.” This study sought to answer: “To what extent has skin‐of‐color representation changed in widely used U.S. medical textbooks over twenty years?” Older and newer editions of four widely used medical textbooks were ...
Justin Lyon, Dillon Stevens, Adriene Pavek, Annabelle Huntsman, Jennifer L. Hamilton   +4 more
wiley   +1 more source

Comment on preparation of an artificial phenocopy of the white axolotl by removal of the pituitaiy gland from genetically black animals

, 1959
Lehman, Harvey Eugene
core  

Video‐Assisted Intralesional Curettage for Invasive Nonmalignant Giant Cell Tumors

Arthroscopy Techniques, EarlyView.
Abstract Giant cell tumor of bone is a locally aggressive benign neoplasm with a strong tendency for local recurrence after surgical treatment. Intralesional excision and curettage is preferred in most cases to maximize tumor removal while preserving the affected joint.
George Loria, Mohamed Ahmed Mohamed, George Alexander Rublev, Irakli Gogua, Giorgi Zimlitski, Mikheil Zimlitski   +5 more
wiley   +1 more source

In vitro model of retinal pigment epithelium for use in drug delivery studies [PDF]

Mannermaa, Eliisa
core