Results 121 to 130 of about 53,576 (289)

Identification and functional validation of a novel disease‐causing variant in the noncoding region of NYX

Acta Ophthalmologica, EarlyView.
Abstract Purpose Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of disorders, with ~30% of cases remaining genetically unsolved. Complete congenital stationary night blindness (cCSNB) is a subtype of IRD, usually associated with reduced visual acuity, nystagmus and high myopia.
Filip Spanic, Christelle Michiels, Julien Navarro, Aline Antonio, Christel Condroyer, Camille Andrieu, Billy Gipsy, Sylvie Berthémy‐Pellet, Mathilde Gallice, Isabelle Audo, Christina Zeitz   +10 more
wiley   +1 more source

Malignancy of Eye Melanomas Originating in the Retinal Pigment Epithelium of Transgenic Mice after Genetic Ablation of Choroidal Melanocytes

, 1992
MALIGNANCY OF EYE MELANOMAS ORIGINATING IN THE RETINAL PIGMENT EPITHELIUM OF TRANSGENIC MICE AFTER GENETIC ABLATION OF CHOROIDAL MELANOCYTES Malignancy of Eye Melanomas Originating in the Retinal Pigment Epithelium of Transgenic Mice after Genetic ...
Mintz, Beatrice Andres J. P. Klein-Szanto
core  

Risk factors for the development of subretinal fluid in the fellow eyes of patients with chronic central serous chorioretinopathy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess the risk of subretinal fluid (SRF) development in the fellow eye of chronic central serous chorioretinopathy (cCSC) patients with unilateral SRF at baseline. Methods Medical records of 334 presumed cCSC patients were retrospectively reviewed.
Helena M. A. Feenstra, Tahir Cakar, Joost Brinks, Camiel J. F. Boon, Elon H. C. van Dijk   +4 more
wiley   +1 more source

Ocular nanoparticle toxicity and transfection of the retina and retinal pigment epithelium

, 2008
Chitosan, PCEP (poly{[(cholesteryl oxocarbonylamido ethyl) methyl bis(ethylene) ammonium iodide] ethyl phosphate}), and magnetic nanoparticles (MNPs) were evaluated for the safe delivery of genes in the eye.
Bhutto, I., Rodriguez, Li, Kim, Sahng Y., Rodriguez, L., Uno, Koichi, Leong, Kam, Greebe, Rhonda, McLeod, D.S., Bhutto, Imran, McLeod, Scott, Lutty, Gerard A., Lutty, G.A., Mennon, Mohamed, Leong, K., Merges, Carol, Grebe, R., Uno, K., Merges, C., Prow, T.W., Kim, S.Y., Mennon, M., Prow, Tarl W.   +21 more
core   +1 more source

The oscillatory response of the electroretinogram and neuronal adaptation

Acta Ophthalmologica, EarlyView.
Abstract After more than 50 years, there still remains a challenge and an interest to know more as well as extend and deepen our understanding of the small rapid wavelets, the oscillatory potentials (OPs), of the electroretinogram (ERG) and the neuronal adaptation of the retina.
Lillemor Wachtmeister, Anders Eklund
wiley   +1 more source

Alterations of iris pigment epithelium by transmission electron microscopy.

, 2019
Electron microscopy of an uninjected eye revealed that the posterior chamber was free of microfibrils (A). Microfibrils emerged from lateral cell invaginations (B), accumulated as aggregates on the epithelial surface (C) and were associated with ...
Yong Yuan (253559), Jianhua Zhang (6347), Winston W.-Y. Kao (43982), Taylor Rice (6429215), Ursula Schlötzer-Schrehardt (283317), Mindy Call (6429209), Fred B. Chu (6429212), Fei Dong (120427), Robert Ritch (839811)   +8 more
core   +1 more source

Long‐term follow‐up of chronic central serous chorioretinopathy patients receiving oral eplerenone and half‐dose photodynamic therapy in the SPECTRA trial: SPECTRA trial report No. 4

Acta Ophthalmologica, EarlyView.
Abstract Purpose Assessing the 24‐month treatment outcome of half‐dose photodynamic therapy (PDT) or oral eplerenone in chronic central serous chorioretinopathy (cCSC). Methods Multicentre randomized clinical trial included cCSC patients from the SPECTRA trial who were randomized to receive half‐dose PDT or oral eplerenone.
Helena M. A. Feenstra, Issam El Mansori, Thomas J. van Rijssen, Roula Tsonaka, Roselie M. H. Diederen, Carel B. Hoyng, Reinier O. Schlingemann, Camiel J. F. Boon, Elon H. C. van Dijk   +8 more
wiley   +1 more source

Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations

Acta Ophthalmologica, EarlyView.
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol, Ana Martínez‐Vacas, David García‐Bernal, Manuel Vidal‐Sanz, María Paz Villegas‐Pérez, Diego García‐Ayuso, Johnny Di Pierdomenico   +6 more
wiley   +1 more source

The optical coherence tomography and microperimetry biomarker evaluation in patients with geographic atrophy (OMEGA) study: Geographic atrophy progression in fundus autofluorescence ‐ OMEGA report 3

Acta Ophthalmologica, EarlyView.
Abstract Purpose To measure the progression of geographic atrophy (GA) in subjects with age‐related macular degeneration (AMD) in a natural history study. Methods We analysed fundus autofluorescence (FAF) images using a semiautomatic method (RegionFinder) to quantify the GA area in a monocentric study.
Philippe Valmaggia, Georg Ansari, Nadja Inglin, Nils Schärer, Hanna Zuche, Chrysoula Gabrani, Faady Yahya, Marco Cattaneo, Kristina Pfau, Andrea Giani, Marieh Esmaeelpour, Taffeta Chingning Yamaguchi, Christian Prünte, Hendrik P. N. Scholl, Nicolas Feltgen, Leopold Schmetterer, Maximilian Pfau, Peter M. Maloca   +17 more
wiley   +1 more source

Upward Extension of an Atrophic Tract of the Retinal Pigment Epithelium Associated with Congenital Macular Toxoplasmosis

, 1999
Purpose To report an unusual case of gravitational atrophic tract of the retinal pigment epithelium in a 20-year old woman. Methods Case report Results The patient had macular cicatricial congenital toxoplasmic chorioretinitis in both eyes.
M. Khairallah, K. Hmidi, S. Ben Yahia, R. Messaoud, A. Ladjimi   +4 more
core   +1 more source