Results 1 to 10 of about 56,052 (118)
Functions and Diseases of the Retinal Pigment Epithelium
Frontiers in Pharmacology, 2021 The retinal pigment epithelium is a fundamental component of the retina that plays essential roles in visual functions. Damage to the structure and function of the retinal pigment epithelium leads to a variety of retinopathies, and there is currently no ...
Song Yang, Dengwen Li, Li Dengwen
exaly +3 more sources
Офтальмохирургия, 2023 Relevance. The retinal pigment epithelium performs a number of highly specialized functions. The relevance of studying morphological changes in the pigment epithelium is associated with an increased number of patients with age-related macular ...
R.R. Fayzrakhmanov +4 more
doaj +1 more source
Advances in the treatment of rhegmatogenous retinal detachment [PDF]
International Journal of Ophthalmology, 2019 The pathogenesis of rhegmatogenous retinal detachment depends on three factors, namely, retinal rupture, vitreous liquefaction and traction causing the retina to separate from the pigment epithelium, among which retinal rupture is the most important ...
Li Liao, Xiao-Hua Zhu
doaj +1 more source
Acta Biomedica Scientifica, 2021 Detachment of the pigment epithelium is the separation of the basement membrane of the retinal pigment epithelium from the inner collagen layer of Bruch’s membrane, which occurs in 80 % of cases in patients with neovascular age-related macular ...
E. V. Kozina +4 more
doaj +1 more source
Scaffolds for retinal pigment epithelial cell transplantation in age-related macular degeneration
Journal of Tissue Engineering, 2017 In several retinal degenerative diseases, including age-related macular degeneration, the retinal pigment epithelium, a highly functionalized cell monolayer, becomes dysfunctional.
Corina E White, Ronke M Olabisi
doaj +1 more source
Journal of Tissue Engineering, 2016 The retinal pigment epithelium is an important part of the vertebrate eye, particularly in studying the causes and possible treatment of age-related macular degeneration.
Aaron H Fronk, Elizabeth Vargis
doaj +1 more source
Basic and Clinical Neuroscience, 2021 Introduction: Neurosphere-free transdifferentiation of bone marrow stem cells into Retinal Pigment Epithelium (RPE) and Retinal Cells (RCs) in vitro could offer an exceptional opportunity to study cell replacement in degenerative eye diseases.
Hamid AboutalebKadkhodaeian +2 more
doaj
eLife, 2017 Here we report multiple lines of evidence for a comprehensive model of energy metabolism in the vertebrate eye. Metabolic flux, locations of key enzymes, and our finding that glucose enters mouse and zebrafish retinas mostly through photoreceptors ...
Mark A Kanow +16 more
doaj +1 more source
Hamartomas of the Retina and Optic Disc
Türk Oftalmoloji Dergisi, 2022 Hamartomas are local malformation of cells that demonstrate abnormal proliferation in the area where they are normally present. Retinal and optic disc hamartomas include astrocytic hamartoma, congenital hypertrophy of the retinal pigment epithelium ...
Ibadulla Mirzayev, Ahmet Kaan Gündüz
doaj +1 more source
Deficiency in Lyst function leads to accumulation of secreted proteases and reduced retinal adhesion
PLoS ONE, 2022 Chediak–Higashi syndrome, caused by mutations in the Lysosome Trafficking Regulator (Lyst) gene, is a recessive hypopigmentation disorder characterized by albinism, neuropathies, neurodegeneration, and defective immune responses, with enlargement of ...
Xiaojie Ji +8 more
doaj +3 more sources