Results 1 to 10 of about 50,869 (165)

The retinal pigment epithelium as a gateway for monocyte trafficking into the eye [PDF]

EMBO Journal, 2016
The choroid plexus epithelium within the brain ventricles orchestrates blood-derived monocyte entry to the central nervous system under injurious conditions, including when the primary injury site is remote from the brain. Here, we hypothesized that the retinal pigment epithelium (RPE) serves a parallel role, as a gateway for monocyte trafficking to ...
Inbal Benhar, Kitty Reemst, Vyacheslav Kalchenko   +2 more
exaly   +3 more sources

Structure and function of the retinal pigment epithelium, photoreceptors and cornea in the eye of Sardinella aurita (Clupeidae, Teleostei)

Journal of Basic and Applied Zoology, 2016
The structure of the pigment epithelium, photoreceptors and the cornea in the eye of a teleost, Sardinella aurita was examined by light and electron microscopy.
Mostafa Ali Salem
doaj   +3 more sources

Preclinical in vivo dosimetry of healthy tissues in radiopharmaceutical therapy: implementation of a physiologically realistic mouse eye model in GATE [PDF]

EJNMMI Research
Background Targeted radionuclide therapy is a rapidly growing treatment modality that has shown great promise in managing metastatic cancers. However, the affinity of certain radiopharmaceuticals for off-target healthy tissues necessitates accurate ...
Elodie Jouberton, Nicolas Sas, Tommy Billoux, Philippe Auzeloux, Sébastien Schmitt, Leslie Mazuel, Jean-Michel Chezal, Elisabeth Miot-Noirault, Isabelle Ranchon-Cole, Florent Cachin   +9 more
doaj   +2 more sources

Setting Eyes on the Retinal Pigment Epithelium [PDF]

Frontiers in Cell and Developmental Biology, 2018
The neural component of the zebrafish eye derives from a small group of cells known as the eye/retinal field. These cells, positioned in the anterior neural plate, rearrange extensively and generate the optic vesicles (OVs). Each vesicle subsequently folds over itself to form the double-layered optic cup, from which the mature eye derives.
Tania Moreno-Marmol, Tania Moreno-Marmol, Florencia Cavodeassi, Paola Bovolenta, Paola Bovolenta   +4 more
openaire   +4 more sources

The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye [PDF]

Pigment Cell Research, 2006
SummaryVertebrate retinal pigment epithelium (RPE) cells are derived from the multipotent optic neuroepithelium, develop in close proximity to the retina, and are indispensible for eye organogenesis and vision. Recent advances in our understanding of RPE development provide evidence for how critical signaling factors operating in dorso‐ventral and ...
Kapil, Bharti, Minh-Thanh T, Nguyen, Susan, Skuntz, Stefano, Bertuzzi, Heinz, Arnheiter   +4 more
openaire   +2 more sources

Idiopathic polypoidal choroidal vasculopathy [PDF]

Vojnosanitetski Pregled, 2012
Background. Idiopathic polypoidal choroidal vasculopathy (IPCV) is uncommon condition. It is considered to be a variant of neovascular age-related macular degeneration, but it can be also found in younger patients. Case report.
Cekić Sonja, Risimić Dijana, Jovanović Ivan, Đorđević-Jocić Jasmina   +3 more
doaj   +1 more source

Antioxidant Defenses in the Human Eye: A Focus on Metallothioneins

Antioxidants, 2021
The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of endogenous and exogenous origin. Oxidative stress affects all structures of the human eye with special emphasis on the ocular surface, the lens, the retina and ...
Ana Álvarez-Barrios, Lydia Álvarez, Montserrat García, Enol Artime, Rosario Pereiro, Héctor González-Iglesias   +5 more
doaj   +1 more source

No association between cataract surgery and mitochondrial DNA damage with age-related macular degeneration in human donor eyes.

PLoS ONE, 2021
PurposeTo determine whether age-related macular degeneration (AMD) severity or the frequency of retinal pigment epithelium mitochondrial DNA lesions differ in human donor eyes that have undergone cataract surgery compared to phakic eyes.MethodsEyes from ...
Karen R Armbrust, Pabalu P Karunadharma, Marcia R Terluk, Rebecca J Kapphahn, Timothy W Olsen, Deborah A Ferrington, Sandra R Montezuma   +6 more
doaj   +1 more source

Co occurrance of Macular Telangiectasia type 2 with hemorrhagic polypoidal choroidal vasculopathy and response to anti-vascular endothelial growth factor

Oman Journal of Ophthalmology, 2023
We report the case of a 57-year-old female patient who presented with defective vision in the right eye due to large hemorrhagic pigment epithelial detachment with subretinal hemorrhage near the arcades with scattered retinal pigment epithelium (RPE ...
Shreyas Shah, George J Manayath, Shruthi Gajula, Venkatapathy Narendran   +3 more
doaj   +1 more source

Presumed Adenocarcinoma of the Retinal Pigment Epithelium in a Blind Eye With a Staphyloma [PDF]

Archives of Ophthalmology, 1998
The retinal pigment epithelium (RPE) can undergo reactive hyperplasia and metaplasia following a variety of ocular insults. However, true neoplasms of the RPE are rare. We report a case of a papillary adenocarcinoma of the RPE arising in the blind staphylomatous right eye of a 79-year-old woman with a long history of bilateral posterior staphylomas who
C, Edelstein, C L, Shields, J A, Shields, R C, Eagle   +3 more
openaire   +2 more sources