Results 41 to 50 of about 53,576 (289)
, 2009 To describe the 2- to 4-year visual and microperimetry outcomes of autologous retinal pigment epithelium (RPE)-choroid graft in patients with neovascular age-related macular degeneration (AMD).In this retrospective cohort study, 12 patients with ...
Coffey, PJ +9 more
core +1 more source
Candidate gene study of macular response to supplemental lutein and zeaxanthin. [PDF]
, 2013 Supplementation with carotenoids is proposed to protect against age-related macular degeneration. There is, however, considerable variability in retinal macular pigment response, which may be due to underlying genetic variation. The purpose of this study
Liew, SH Melissa +15 more
core +1 more source
Unilateral pigment dispersion syndrome
PAMJ Clinical Medicine, 2020 A 40-year-old woman who presented for prescription of glasses. She had no history of ocular trauma, inflammation, or any ocular disease. Refraction was - 1,25D in the right eye, and -1 in the left eye. Corrected Visual acuity was 6/6 in both eyes.
Taoufik Abdellaoui, Abdelbarre Oubaaz
doaj +1 more source
Case Reports in Ophthalmology, 2020 We experienced a case of subretinal hemorrhage (SRH) from choroidal neovascularization (CNV) complicating Vogt-Koyanagi-Harada disease (VKH) that underwent pneumatic displacement of hematoma by intravitreal gas injection.
Takatoshi Kobayashi +7 more
doaj +1 more source
The retinal pigment epithelium of the eye regulates the development of scleral cartilage
Developmental Biology, 2010 The majority of vertebrate species have a layer of hyaline cartilage within the fibrous sclera giving an extra degree of support to the eyeball. In chicks, this is seen as a cuplike structure throughout the scleral layer. However, the mechanisms that control the development of scleral cartilage are largely unknown.
Thompson, H +3 more
openaire +3 more sources
Nature Communications, 2022 Age-related macular degeneration (AMD) is a leading cause of blindness and is characterised by the accumulation of lipid deposits, called drusen. Here, the authors show that mice lacking chloride intracellular channel 4 in retinal pigment epithelium have
Jen-Zen Chuang +13 more
doaj +1 more source
Delhi Journal of Ophthalmology, 2021 A young male patient presented with history of blunt injury to his left eye with defective vision. His fundus examination showed commotio-retinae inferiorly associated with Berlinʼs oedema.
Prasanna Venkatesh Ramesh +3 more
doaj +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Long-Term Follow-Up of Congenital Simple Hamartoma of the Retinal Pigment Epithelium: A Case Report
Case Reports in Ophthalmology, 2018 Background: Congenital simple hamartoma of the retinal pigment epithelium (CSHRPE) is a rare benign tumor of the retinal pigment epithelium characterized by a focal, darkly pigmented nodule in the macular lesion in healthy persons.
Yuka Ito, Masahito Ohji
doaj +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
FEBS Open Bio, EarlyView.Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source