Results 41 to 50 of about 50,998 (262)

Dexamethasone Increases Pigment Epithelium-Derived Factor in Perfused Human Eyes [PDF]

Current Eye Research, 2008
To investigate the effects of dexamethasone (DEX) on pigment epithelium-derived factor (PEDF) cDNA and secreted protein in human trabecular meshwork (TM).
Elizabeth M, Perruccio, Laura Leigh S, Rowlette, Nuria, Comes, Silvia, Locatelli-Hoops, Luigi, Notari, S Patricia, Becerra, Teresa, Borrás   +6 more
openaire   +2 more sources

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

Giant retinal pigment epithelium tears with membranous nephropathy: a case report and literature review

BMC Ophthalmology
Background Kidney and eye diseases may be closely linked. Tears of the retinal pigment epithelium (RPE) have been reported to be related to kidney diseases, such as IgA nephropathy and light-chain deposition disease.
Rui Dou, Yanhua Chu, Quanhong Han, Wei Zhang, Xue Bi   +4 more
doaj   +1 more source

Negotiating in a Foreign Land: Understanding the Curious Interactions Between Intracellular Mitochondria and Internalized Nanoparticles

Advanced Materials Interfaces, EarlyView.
Therapeutic nano‐drug delivery systems interact with cellular mitochondria in a multitude of ways. While the complexity of such interactions disrupts the mitochondrial electron transport chain and increases reactive oxygen species production, thereby contributing to nanoparticle toxicity, they also present unique theranostic opportunities in diseases ...
Sourav Bhattacharjee
wiley   +1 more source

Comparative evaluation of melanin content in melanosomes and melanolipofuscin granules from the human retinal pigment epithelium cells

Офтальмохирургия, 2018
Purpose. Comparative study of the melanin content in melanosomes and melanolipofuscin granules from cells of the retinal pigment epithelium of the human eye. Material and methods.
N. L. Sakina, A. E. Dontsov, E. N. Degtyarev, A. L. Kovarsky, P. M. Arbukhanova, S. A. Borzenok, M. A. Ostrovsky   +6 more
doaj   +1 more source

The distribution of toxic metals in the human retina and optic nerve head: Implications for age-related macular degeneration.

PLoS ONE, 2020
ObjectiveToxic metals are suspected to play a role in the pathogenesis of age-related macular degeneration. However, difficulties in detecting the presence of multiple toxic metals within the intact human retina, and in separating primary metal toxicity ...
Roger Pamphlett, Svetlana Cherepanoff, Lay Khoon Too, Stephen Kum Jew, Philip A Doble, David P Bishop   +5 more
doaj   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

Advanced Materials Technologies, EarlyView.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le, Anh Tuan Trong Tran, Ammara Waheed, Tran Thanh Tung, Dusan Losic   +4 more
wiley   +1 more source

Effect of radio frequency with different temperatures in histologic structure of Garra rufa eye [PDF]

مجلة التربية والعلم, 2010
The present study carried out to investigate the injuries caused by 50KHz radiofrequency at 1200 V on the histological components of the eye of Garra rufa fish.
Ali Abdul, Sanabel Abdel Majeed
doaj   +1 more source

A Pentaradial and Bilateral Combined Photoreception System in the Sea Cucumber is Mediated by a Blue Light‐Sensitive R‐Opsin

Advanced Science, EarlyView.
The sea cucumber Holothuria leucospilota detects blue and adjacent wavelengths of light via an r‐opsin with a maximum absorption at 459 nm. In the oral tentacles, papillae, and tube feet, distinct light‐sensing structures with specialized morphologies are formed, constituting a unique pentaradial and bilateral combined photoreception system.
Jiasheng Huang, Chunhua Ren, Zhou Qin, Yimeng Cui, Bingbing Zhang, Peng Luo, Xuan Wang, Yaoqi Xie, Xin Zhang, Aifen Yan, Yang Zhang, Dingding Fan, Yang Liu, Wenjie Pan, Xiao Jiang, Lihong Yuan, Haipeng Qin, David M. Irwin, Chaoqun Hu, Yang Liu, Ting Chen   +20 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source