Results 31 to 40 of about 50,998 (262)

Unilateral pigment dispersion syndrome

open access: yesPAMJ Clinical Medicine, 2020
A 40-year-old woman who presented for prescription of glasses. She had no history of ocular trauma, inflammation, or any ocular disease. Refraction was - 1,25D in the right eye, and -1 in the left eye. Corrected Visual acuity was 6/6 in both eyes.
Taoufik Abdellaoui, Abdelbarre Oubaaz
doaj   +1 more source

The retinal pigment epithelium of the eye regulates the development of scleral cartilage

open access: yesDevelopmental Biology, 2010
The majority of vertebrate species have a layer of hyaline cartilage within the fibrous sclera giving an extra degree of support to the eyeball. In chicks, this is seen as a cuplike structure throughout the scleral layer. However, the mechanisms that control the development of scleral cartilage are largely unknown.
Thompson, H   +3 more
openaire   +3 more sources

Retinal pigment epithelium-specific CLIC4 mutant is a mouse model of dry age-related macular degeneration

open access: yesNature Communications, 2022
Age-related macular degeneration (AMD) is a leading cause of blindness and is characterised by the accumulation of lipid deposits, called drusen. Here, the authors show that mice lacking chloride intracellular channel 4 in retinal pigment epithelium have
Jen-Zen Chuang   +13 more
doaj   +1 more source

Optical Coherence Tomography Findings Of Photoreceptor-Retinal Pigment Epithelium Complex In Acute Traumatic Maculopathy

open access: yesDelhi Journal of Ophthalmology, 2021
A young male patient presented with history of blunt injury to his left eye with defective vision. His fundus examination showed commotio-retinae inferiorly associated with Berlinʼs oedema.
Prasanna Venkatesh Ramesh   +3 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Coexistence of Optic Nerve Head Drusen and Combined Hamartoma of the Retina and Retinal Pigment Epithelium in a Taiwanese Male

open access: yesKaohsiung Journal of Medical Sciences, 2009
We report the case of a 38-year-old male patient with a 1-year history of progressively blurred vision in his left eye. He visited our clinic and underwent a series of ophthalmologic examinations including computed tomography, fluorescein angiography and
Yo-Chen Chang, Rong-Kung Tsai
doaj   +1 more source

Multifunctional Catechol‐Functionalized Cellulose Hydrogels for the Minimally Invasive Treatment of Acute Optic Nerve Injuries

open access: yesAdvanced Healthcare Materials, EarlyView.
Catechol‐functionalized cellulose hydrogels are developed as injectable, bioadhesive platforms for retinal neuroprotection. The hydrogels exhibit tunable rheological and mechanical properties, strong tissue adhesion, and sustained antioxidative activity.
Kai‐Hsiang Chang   +4 more
wiley   +1 more source

Long-Term Follow-Up of Congenital Simple Hamartoma of the Retinal Pigment Epithelium: A Case Report

open access: yesCase Reports in Ophthalmology, 2018
Background: Congenital simple hamartoma of the retinal pigment epithelium (CSHRPE) is a rare benign tumor of the retinal pigment epithelium characterized by a focal, darkly pigmented nodule in the macular lesion in healthy persons.
Yuka Ito, Masahito Ohji
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer   +12 more
wiley   +1 more source

Superior cervical gangliectomy induces non-exudative age-related macular degeneration in mice

open access: yesDisease Models & Mechanisms, 2018
Non-exudative age-related macular degeneration, a prevalent cause of blindness, is a progressive and degenerative disease characterized by alterations in Bruch's membrane, retinal pigment epithelium, and photoreceptors exclusively localized in the macula.
Hernán H. Dieguez   +6 more
doaj   +1 more source

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