Results 11 to 20 of about 52,550 (248)

Setting Eyes on the Retinal Pigment Epithelium [PDF]

Frontiers in Cell and Developmental Biology, 2018
The neural component of the zebrafish eye derives from a small group of cells known as the eye/retinal field. These cells, positioned in the anterior neural plate, rearrange extensively and generate the optic vesicles (OVs). Each vesicle subsequently folds over itself to form the double-layered optic cup, from which the mature eye derives.
Tania Moreno-Marmol, Tania Moreno-Marmol, Florencia Cavodeassi, Paola Bovolenta, Paola Bovolenta   +4 more
openaire   +4 more sources

The other pigment cell: specification and development of the pigmented epithelium of the vertebrate eye [PDF]

Pigment Cell Research, 2006
SummaryVertebrate retinal pigment epithelium (RPE) cells are derived from the multipotent optic neuroepithelium, develop in close proximity to the retina, and are indispensible for eye organogenesis and vision. Recent advances in our understanding of RPE development provide evidence for how critical signaling factors operating in dorso‐ventral and ...
Kapil, Bharti, Minh-Thanh T, Nguyen, Susan, Skuntz, Stefano, Bertuzzi, Heinz, Arnheiter   +4 more
openaire   +2 more sources

Idiopathic polypoidal choroidal vasculopathy [PDF]

Vojnosanitetski Pregled, 2012
Background. Idiopathic polypoidal choroidal vasculopathy (IPCV) is uncommon condition. It is considered to be a variant of neovascular age-related macular degeneration, but it can be also found in younger patients. Case report.
Cekić Sonja, Risimić Dijana, Jovanović Ivan, Đorđević-Jocić Jasmina   +3 more
doaj   +1 more source

Antioxidant Defenses in the Human Eye: A Focus on Metallothioneins

Antioxidants, 2021
The human eye, the highly specialized organ of vision, is greatly influenced by oxidants of endogenous and exogenous origin. Oxidative stress affects all structures of the human eye with special emphasis on the ocular surface, the lens, the retina and ...
Ana Álvarez-Barrios, Lydia Álvarez, Montserrat García, Enol Artime, Rosario Pereiro, Héctor González-Iglesias   +5 more
doaj   +1 more source

No association between cataract surgery and mitochondrial DNA damage with age-related macular degeneration in human donor eyes.

PLoS ONE, 2021
PurposeTo determine whether age-related macular degeneration (AMD) severity or the frequency of retinal pigment epithelium mitochondrial DNA lesions differ in human donor eyes that have undergone cataract surgery compared to phakic eyes.MethodsEyes from ...
Karen R Armbrust, Pabalu P Karunadharma, Marcia R Terluk, Rebecca J Kapphahn, Timothy W Olsen, Deborah A Ferrington, Sandra R Montezuma   +6 more
doaj   +1 more source

Co occurrance of Macular Telangiectasia type 2 with hemorrhagic polypoidal choroidal vasculopathy and response to anti-vascular endothelial growth factor

Oman Journal of Ophthalmology, 2023
We report the case of a 57-year-old female patient who presented with defective vision in the right eye due to large hemorrhagic pigment epithelial detachment with subretinal hemorrhage near the arcades with scattered retinal pigment epithelium (RPE ...
Shreyas Shah, George J Manayath, Shruthi Gajula, Venkatapathy Narendran   +3 more
doaj   +1 more source

Presumed Adenocarcinoma of the Retinal Pigment Epithelium in a Blind Eye With a Staphyloma [PDF]

Archives of Ophthalmology, 1998
The retinal pigment epithelium (RPE) can undergo reactive hyperplasia and metaplasia following a variety of ocular insults. However, true neoplasms of the RPE are rare. We report a case of a papillary adenocarcinoma of the RPE arising in the blind staphylomatous right eye of a 79-year-old woman with a long history of bilateral posterior staphylomas who
C, Edelstein, C L, Shields, J A, Shields, R C, Eagle   +3 more
openaire   +2 more sources

Type 3 Neovascularization Associated with Retinitis Pigmentosa

Case Reports in Ophthalmology, 2017
Purpose: To report a case of type 3 neovascular lesion in a patient with retinitis pigmentosa (RP) complicated by macular edema. Case Report: A 78-year-old man with a long follow-up for RP was referred for painless visual acuity decrease in the right eye.
Jihene Sayadi, Alexandra Miere, Eric H. Souied, Salomon Y. Cohen   +3 more
doaj   +1 more source

Dissection of a Mouse Eye for a Whole Mount of the Retinal Pigment Epithelium [PDF]

Journal of Visualized Experiments, 2011
The retinal pigment epithelium (RPE) lies at the back of the mammalian eye, just under the neural retina, which contains the photoreceptors (rods and cones). The RPE is a monolayer of pigmented cuboidal cells and associates closely with the neural retina just above it.
Alison, Claybon, Alexander J R, Bishop
openaire   +2 more sources

Methods for culturing retinal pigment epithelial cells: a review of current protocols and future recommendations

Journal of Tissue Engineering, 2016
The retinal pigment epithelium is an important part of the vertebrate eye, particularly in studying the causes and possible treatment of age-related macular degeneration.
Aaron H Fronk, Elizabeth Vargis
doaj   +1 more source