Results 51 to 60 of about 52,550 (248)

Giant retinal pigment epithelium tears with membranous nephropathy: a case report and literature review

BMC Ophthalmology
Background Kidney and eye diseases may be closely linked. Tears of the retinal pigment epithelium (RPE) have been reported to be related to kidney diseases, such as IgA nephropathy and light-chain deposition disease.
Rui Dou, Yanhua Chu, Quanhong Han, Wei Zhang, Xue Bi   +4 more
doaj   +1 more source

Superior cervical gangliectomy induces non-exudative age-related macular degeneration in mice

Disease Models & Mechanisms, 2018
Non-exudative age-related macular degeneration, a prevalent cause of blindness, is a progressive and degenerative disease characterized by alterations in Bruch's membrane, retinal pigment epithelium, and photoreceptors exclusively localized in the macula.
Hernán H. Dieguez, Horacio E. Romeo, María F. González Fleitas, Marcos L. Aranda, Georgia A. Milne, Ruth E. Rosenstein, Damián Dorfman   +6 more
doaj   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Comparative evaluation of melanin content in melanosomes and melanolipofuscin granules from the human retinal pigment epithelium cells

Офтальмохирургия, 2018
Purpose. Comparative study of the melanin content in melanosomes and melanolipofuscin granules from cells of the retinal pigment epithelium of the human eye. Material and methods.
N. L. Sakina, A. E. Dontsov, E. N. Degtyarev, A. L. Kovarsky, P. M. Arbukhanova, S. A. Borzenok, M. A. Ostrovsky   +6 more
doaj   +1 more source

The distribution of toxic metals in the human retina and optic nerve head: Implications for age-related macular degeneration.

PLoS ONE, 2020
ObjectiveToxic metals are suspected to play a role in the pathogenesis of age-related macular degeneration. However, difficulties in detecting the presence of multiple toxic metals within the intact human retina, and in separating primary metal toxicity ...
Roger Pamphlett, Svetlana Cherepanoff, Lay Khoon Too, Stephen Kum Jew, Philip A Doble, David P Bishop   +5 more
doaj   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Effect of radio frequency with different temperatures in histologic structure of Garra rufa eye [PDF]

مجلة التربية والعلم, 2010
The present study carried out to investigate the injuries caused by 50KHz radiofrequency at 1200 V on the histological components of the eye of Garra rufa fish.
Ali Abdul, Sanabel Abdel Majeed
doaj   +1 more source

Neuromorphic Devices and Computing for Sensing, Memory, and Control

Advanced Science, EarlyView.
This review introduces neuromorphic devices made from diverse materials. These devices mimic neuronal functions and architectures and, when integrated with artificial or biological computing, can form closed loops with neurons for pressure, optical, acoustic, and biochemical sensing and modulation.
Zhengguang Zhu, Nicholas Schaffer, Xiao Yang   +2 more
wiley   +1 more source

Retinal pigment epithelium condition after laser and ultrasound phacofragmentation. Electron microscopy in experiment. Report 1

Офтальмохирургия, 2013
Purpose. To perform a comparative evaluation of a macular retinal pigment epithelium condition after laser and ultrasound phacofragmentations in experiment. Material and method.
S.Y. Kopayev, V.G. Kopayeva, S.A. Borsenok,, V.U. Alborova   +3 more
doaj  

Clinicopathological correlation of parapapillary atrophy in monkeys with experimental glaucoma and temporary central retinal artery occlusion

Indian Journal of Ophthalmology, 2014
Objective: To investigate the clinicopathological correlation of parapapillary atrophy. Materials and Methods: The study included 16 eyes of rhesus monkeys (Macaca mulatta) - 4 eyes with experimental glaucoma, 11 eyes after experimental temporary ...
Jost B Jonas, Sohan S Hayreh, Yong Tao
doaj   +1 more source