Results 21 to 30 of about 66,016 (272)

Spectral optical coherence tomography findings in an elderly patient with syphilitic bilateral chronic panuveitis

American Journal of Ophthalmology Case Reports, 2018
Purpose: To report the spectral domain optical coherence tomography (SD-OCT) features of a focal retinitis in an elderly male patient with bilateral syphilitic panuveitis.
Ariel Schlaen, Mariana Ingolotti, Cristobal Couto, Mario Saravia   +3 more
doaj   +1 more source

Common clinical features of unilateral retinal pigment epithelium dysgenesis and combined hamartoma of the retina and retinal pigment epithelium

BMC Ophthalmology, 2022
Background Herein, we report two cases of unilateral retinal pigment epithelium dysgenesis (URPED) in Chinese patients and explore the relationship between URPED and combined hamartoma of the retina and retinal pigment epithelium (CHRRPE).
Zhe Zhu, Jun Xiao, Lifu Luo, Bo Yang, He Zou, Chenchen Zhang   +5 more
doaj   +1 more source

Evaluation of an Intravitreal Rho-Associated Kinase Inhibitor Depot Formulation in a Rat Model of Diabetic Retinopathy

Pharmaceutics, 2021
Rho-associated kinase (ROCK) activation was shown to contribute to microvascular closure, retinal hypoxia, and to retinal pigment epithelium (RPE) barrier disruption in a rat model of diabetic retinopathy.
Cecile Lebon, Heike Neubauer, Marianne Berdugo, Kimberley Delaunay, Elke Markert, Kolja Becker, Katja S. Baum-Kroker, Jürgen Prestle, Holger Fuchs, Remko A. Bakker, Francine Behar-Cohen   +10 more
doaj   +1 more source

Alterations of retinal thickness measured by optical coherence tomography correlate with neurophysiological measures in diabetic polyneuropathy

Journal of Diabetes Investigation, 2021
Aims/Introduction Diabetic polyneuropathy (DPN) and diabetic retinopathy (DR) are traditionally regarded as microvascular complications. However, these complications may share similar neurodegenerative pathologies.
Yuichiro Yamada, Tatsuhito Himeno, Kotaro Tsuboi, Yuka Shibata, Miyuka Kawai, Yuriko Asada‐Yamada, Yusuke Hayashi, Emi Asano‐Hayami, Tomohide Hayami, Yuichiro Ishida, Yohei Ejima, Mikio Motegi, Saeko Asano, Makoto Kato, Eriko Nagao, Hiromi Nakai‐Shimoda, Takahiro Ishikawa, Yoshiaki Morishita, Masaki Kondo, Shin Tsunekawa, Yoshiro Kato, Takayuki Nakayama, Motohiro Kamei, Jiro Nakamura, Hideki Kamiya   +24 more
doaj   +1 more source

Foveal simple hamartoma of retinal pigment epithelium

TNOA Journal of Ophthalmic Science and Research, 2018
Congenital anomalies of retinal pigment epithelium (RPE) are rare entities among which simple hamartoma of RPE is extremely rare. Majority of reported cases of congenital simple hamartoma were extrafoveal and patients were asymptomatic. These lesions may
Prabu Baskaran, Nagesha Chokahalli, Pratyusha Ganne   +2 more
doaj   +1 more source

Long term evolution of combined hamartoma of the retina and retinal pigment epithelium

Vision Pan-America, 2014
Combined hamartoma of the retina and of the retinal pigment epithelium are extremely rare benign tumors distinguished by retinal pigment epithelium (RPE) and glial tissue proliferation, provoking severe peripapillary and retinal distortion ...
Miriam García Fernández, Joaquín Castro Navarro   +1 more
doaj   +1 more source

Long-term visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration

, 2009
To describe the 2- to 4-year visual and microperimetry outcomes of autologous retinal pigment epithelium (RPE)-choroid graft in patients with neovascular age-related macular degeneration (AMD).In this retrospective cohort study, 12 patients with ...
Coffey, PJ, Uppal, GS, Rubin, GS, Chen, FK, Tufail, A, Maclaren, Robert, Franzco, FKC, Aylward, GW, Da Cruz, L, MacLaren, RE   +9 more
core   +1 more source

A Single-Cell Transcriptome Atlas of the Human Retinal Pigment Epithelium

Frontiers in Cell and Developmental Biology, 2021
Human retinal pigment epithelium cells are arranged in a monolayer that plays an important supporting role in the retina. Although the heterogeneity of specific retinal cells has been well studied, the diversity of hRPE cells has not been reported. Here,
Zongren Xu, Zongren Xu, Zongren Xu, Zongren Xu, Xingyun Liao, Xingyun Liao, Xingyun Liao, Xingyun Liao, Na Li, Hongxiu Zhou, Hongxiu Zhou, Hongxiu Zhou, Hong Li, Hong Li, Hong Li, Qi Zhang, Qi Zhang, Qi Zhang, Ke Hu, Ke Hu, Ke Hu, Peizeng Yang, Peizeng Yang, Peizeng Yang, Peizeng Yang, Shengping Hou, Shengping Hou, Shengping Hou, Shengping Hou   +28 more
doaj   +1 more source

Humanin Mitigates Aβ-Induced Retinal Pigment Epithelium Injury via AMPK-Beclin1-Dependent Mitophagy. [PDF]

Aging Cell
Humanin (HN) enhanced the clearance of Aβ‐accumulated mitochondria in the RPE while preserving retinal function and RPE barrier integrity. HN activated AMP‐activated protein kinase (AMPK), leading to phosphorylation of ULK1 and Beclin1, which promoted the interaction between Beclin1 and Parkin and their translocation to mitochondria.
Jang HY, Choi S, Kim SJ, Kim S, Jo DH, Lee TG, Park KS, Kim JH.   +7 more
europepmc   +2 more sources

Histologic findings following retinal pigment epithelium removal using 8 microsecond laser pulses

, 2023
In the treatment of various retinal pigment epithelium (RPE) related retinal diseases, selective retina therapy (SRT) is highly demanded, as SRT intends to selectively damage the RPE while sparing the neurosensory retina (NSR) and the choroid.
Farese, Gerardo, Huang, Zhiwei, Schulz, André, Al-Nawaiseh, Sami, Meier, Christoph, Salzmann, Simon Adrian, Lilge, Lothar D., Wakili, Philip, Enzmann, Volker, Burri, Christian, Stanzel, Boris, Frenz, Martin, Schweri-Olac, Anelia, Povazay, Boris   +13 more
core   +1 more source