Results 21 to 30 of about 450,341 (256)

Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]

, 2012
The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Johannes Burger, Yu, Alice L., Burger, Johannes, Welge-Lussen, Ulrich, Alice L Yu, Kerstin Birke, Birke, Kerstin, Alice L. Yu, Ulrich Welge-Lussen   +8 more
core   +2 more sources

Spectral optical coherence tomography findings in an elderly patient with syphilitic bilateral chronic panuveitis

American Journal of Ophthalmology Case Reports, 2018
Purpose: To report the spectral domain optical coherence tomography (SD-OCT) features of a focal retinitis in an elderly male patient with bilateral syphilitic panuveitis.
Ariel Schlaen, Mariana Ingolotti, Cristobal Couto, Mario Saravia   +3 more
doaj   +1 more source

Common clinical features of unilateral retinal pigment epithelium dysgenesis and combined hamartoma of the retina and retinal pigment epithelium

BMC Ophthalmology, 2022
Background Herein, we report two cases of unilateral retinal pigment epithelium dysgenesis (URPED) in Chinese patients and explore the relationship between URPED and combined hamartoma of the retina and retinal pigment epithelium (CHRRPE).
Zhe Zhu, Jun Xiao, Lifu Luo, Bo Yang, He Zou, Chenchen Zhang   +5 more
doaj   +1 more source

Evaluation of an Intravitreal Rho-Associated Kinase Inhibitor Depot Formulation in a Rat Model of Diabetic Retinopathy

Pharmaceutics, 2021
Rho-associated kinase (ROCK) activation was shown to contribute to microvascular closure, retinal hypoxia, and to retinal pigment epithelium (RPE) barrier disruption in a rat model of diabetic retinopathy.
Cecile Lebon, Heike Neubauer, Marianne Berdugo, Kimberley Delaunay, Elke Markert, Kolja Becker, Katja S. Baum-Kroker, Jürgen Prestle, Holger Fuchs, Remko A. Bakker, Francine Behar-Cohen   +10 more
doaj   +1 more source

Adult limbal neurosphere cells: a potential autologous cell resource for retinal cell generation [PDF]

, 2014
The Corneal limbus is a readily accessible region at the front of the eye, separating the cornea and sclera. Neural colonies (neurospheres) can be generated from adult corneal limbus in vitro.
Jessica Cooke (637632), Jennifer Scott, Heather Thomson, Xiaoli Chen, Lotery, Andrew J., Xiaoli Chen (102563), Cooke, J.J., Scott, Jennifer A., Andrew Lotery, Heather Thomson (637631), Thomson, Heather, Jessica Cooke, Parwez Hossain, Jennifer Scott (637633), Chen, Xiaoli, Hossain, Parwez, Andrew Lotery (637635), Parwez Hossain (637634)   +17 more
core   +1 more source

Foveal simple hamartoma of retinal pigment epithelium

TNOA Journal of Ophthalmic Science and Research, 2018
Congenital anomalies of retinal pigment epithelium (RPE) are rare entities among which simple hamartoma of RPE is extremely rare. Majority of reported cases of congenital simple hamartoma were extrafoveal and patients were asymptomatic. These lesions may
Prabu Baskaran, Nagesha Chokahalli, Pratyusha Ganne   +2 more
doaj   +1 more source

Alterations of retinal thickness measured by optical coherence tomography correlate with neurophysiological measures in diabetic polyneuropathy

Journal of Diabetes Investigation, 2021
Aims/Introduction Diabetic polyneuropathy (DPN) and diabetic retinopathy (DR) are traditionally regarded as microvascular complications. However, these complications may share similar neurodegenerative pathologies.
Yuichiro Yamada, Tatsuhito Himeno, Kotaro Tsuboi, Yuka Shibata, Miyuka Kawai, Yuriko Asada‐Yamada, Yusuke Hayashi, Emi Asano‐Hayami, Tomohide Hayami, Yuichiro Ishida, Yohei Ejima, Mikio Motegi, Saeko Asano, Makoto Kato, Eriko Nagao, Hiromi Nakai‐Shimoda, Takahiro Ishikawa, Yoshiaki Morishita, Masaki Kondo, Shin Tsunekawa, Yoshiro Kato, Takayuki Nakayama, Motohiro Kamei, Jiro Nakamura, Hideki Kamiya   +24 more
doaj   +1 more source

Long term evolution of combined hamartoma of the retina and retinal pigment epithelium

Vision Pan-America, 2014
Combined hamartoma of the retina and of the retinal pigment epithelium are extremely rare benign tumors distinguished by retinal pigment epithelium (RPE) and glial tissue proliferation, provoking severe peripapillary and retinal distortion ...
Miriam García Fernández, Joaquín Castro Navarro   +1 more
doaj   +1 more source

A Single-Cell Transcriptome Atlas of the Human Retinal Pigment Epithelium

Frontiers in Cell and Developmental Biology, 2021
Human retinal pigment epithelium cells are arranged in a monolayer that plays an important supporting role in the retina. Although the heterogeneity of specific retinal cells has been well studied, the diversity of hRPE cells has not been reported. Here,
Zongren Xu, Zongren Xu, Zongren Xu, Zongren Xu, Xingyun Liao, Xingyun Liao, Xingyun Liao, Xingyun Liao, Na Li, Hongxiu Zhou, Hongxiu Zhou, Hongxiu Zhou, Hong Li, Hong Li, Hong Li, Qi Zhang, Qi Zhang, Qi Zhang, Ke Hu, Ke Hu, Ke Hu, Peizeng Yang, Peizeng Yang, Peizeng Yang, Peizeng Yang, Shengping Hou, Shengping Hou, Shengping Hou, Shengping Hou   +28 more
doaj   +1 more source

Advances in the study of tissue-engineered retinal pigment epithelial cell sheets

Regenerative Therapy
Regarded as the most promising treatment modality for retinal degenerative diseases, retinal pigment epithelium cell replacement therapy holds significant potential.
Wang Zhou, Yujiao Chai, Shan Lu, Qiaohui Yang, Liying Tang, Di Zhou   +5 more
doaj   +1 more source