Results 171 to 180 of about 50,998 (262)

The Host Cell Factor Phosphatase‐2A Subunit PR130 Restricts Replication of Herpes Simplex Virus Type‐1

Advanced Science, Volume 13, Issue 44, 7 August 2026.
Molecular, genetic, virological, and biochemical analysis in combination with global proteome and phosphoproteome profiling and functional assays were applied to study the role of PR130 in the context of HSV‐1 replication. The observations reveal that host‐intrinsic mechanisms regulate HSV‐1 replication and highlight PR130 as a susceptibility factor of
Johannes Jungwirth, Christoph F. Jacob, Alexandra Nguyen, Mandy Beyer, Andreas O. Mieland, Mario Dejung, Jia‐Xuan Chen, Walburgis Brenner, Christina Ehrhardt, Andreas Henke, Oliver H. Krämer   +10 more
wiley   +1 more source

IN VIVO SURGICAL APPROACH OF SUBRETINAL CYSTICERCOSIS: A CASE REPORT. [PDF]

Retin Cases Brief Rep
Medina Melo MM, Quintero Arciniegas L, Morales Orozco S.   +2 more
europepmc   +1 more source

CLRN1 Variants in Müller Cells Cause Mitochondrial Dysfunction in USH3A Retinal Organoids

CNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
We generated retinal organoids from a patient with USH3A and performed single‐cell RNA sequencing. CLRN1 was specifically expressed in Müller cells, where its variants led to mitochondrial dysfunction and photoreceptor degeneration. ABSTRACT Background Usher syndrome 3A (USH3A), caused by mutations in the CLRN1 gene, leads to retinitis pigmentosa and ...
Rui Zhang, Xinbo Ji, Han Yu, Jingwen Xu, Yu Wang, Ping Sun, Yingxin Wang, Yao Tang, Zexin Zhan, Yichang Jiao, Didi Shan, Pengfei Lin, Dong‐dong Wang, Yuying Zhao, Xianyang Liu, Chuanzhu Yan, Jianqiao Li, Mingfeng Li, Fuchen Liu, Shengping Hou   +19 more
wiley   +1 more source

Targeting Macular Pigment in Intermediate Age-Related Macular Degeneration: Oral Supplementation Versus Transscleral Iontophoresis in a Prospective Pilot Study. [PDF]

J Clin Med
Rinaldi M, Cennamo G, Passaro ML, Chiosi F, Falco F, D'Alessandro A, Strianese D, Costagliola C.   +7 more
europepmc   +1 more source

Applications of Bioinorganic Nano‐Based Delivery Systems—Diagnostics and Therapeutics

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Nanotechnology has emerged as a promising avenue for producing nanomedicines as alternatives to conventional drugs. Many organic nanoparticles, such as liposomes used in formulations like Doxil, Onivyde, and Marqibo, are approved by the Food and Drug Administration (FDA) and instrumental in treating various types of cancers.
Frank Ssengooba, Jubilee Andrew, Donald Fernandes   +2 more
wiley   +1 more source

Pathways to Patchy Atrophy in High Myopia: Precursor Patterns, Structural Characteristics, and Long-Term Outcomes. [PDF]

Ophthalmol Sci
Del Fabbro S, Jonas JB, Panda-Jonas S, Motloch K, Cicinelli MV, Battaglia Parodi M, Miserocchi E, Couturier A, Philippakis E.   +8 more
europepmc   +1 more source

Moutan Cortex Extract Mediates Diabetic Retinopathy by Blocking the ROS‑Triggered HIF‐1α/VEGF Axis in Retinal Pigment Epithelial Cells

eFood, Volume 7, Issue 4, August 2026.
Schematic diagram of the mechanism by which Moutan Cortex extract (MCE) ameliorates DR. MCE alleviates retinal structural damage and reduces neovascular lesions by downregulating the ROS/HIF‐1α/VEGF signaling axis. ABSTRACT Moutan Cortex is a functional food ingredient with multiple health benefits, but its effects on diabetic retinopathy (DR) remain ...
Mei‐rong Li, Xian‐yi Zhang, Wan‐ying Zhang, Nan Chen, Wei‐wei Lv, Tian‐yu Liu, Xu Guo, Ying‐ying Chen, Meng‐qi Zhang, Shu‐tao Sun, Mu‐xuan Wang, Qi‐dong Ren, Chao Liu, Jin‐yue Sun   +13 more
wiley   +1 more source

Use of Simultaneous Emission of Nd:YAG and Alexandrite Lasers in BLEND Mode for Hair Removal and Permanent Hair Reduction

Lasers in Surgery and Medicine, Volume 58, Issue 6, Page 462-473, August 2026.
Abstract Objective To evaluate the safety, efficacy, and patient satisfaction of a novel laser technology that employs simultaneous emission of Alexandrite (755 nm) and Nd:YAG (1064 nm) wavelengths for permanent hair removal, as compared with standard of care treatment using a single wavelength (either Alexandrite or Nd:Yag).
Nkemjika Ugonabo, Anne M. Chapas, Thomas E. Rohrer   +2 more
wiley   +1 more source

Paired DNA and RNA sequencing uncovers common and rare variation regulating human retinal gene expression. [PDF]

Nat Commun
Sampson J, Segrè AV, Bujakowska KM, Clark SJ, Bishop PN, Haynes S, Baralle D, Al-Deek J, Holden S, Anderson B, Hayes A, Kemal RA, Thomas HB, O'Keefe RT, Banka S, Black GC, Sergouniotis PI, Ellingford JM.   +17 more
europepmc   +1 more source

Development and Characterization of a Structurally Supportive of Hybrid PLGA Decellularized ECM Biomembrane for Ocular Progenitor Cell Anchorage and Epithelial Repair

Macromolecular Bioscience, Volume 26, Issue 8, August 2026.
Hybrid PLGA–corneal ECM biomembrane for ocular progenitor cell support and progenitor retinal cytoprotection. A hybrid biomembrane composed of PLGA and decellularized corneal extracellular matrix was developed to create a biomimetic microenvironment for ocular progenitor cells.
Ana Karulline Garcia Ungaratti, Aliny Pereira de Lima, Jordana Andrade Santos, Paula Leticia de Melo, Daniel Graziani, Artur Christian G. da Silva, Luis Antônio Dantas Silva, Marize Campos Valadares   +7 more
wiley   +1 more source