Results 51 to 60 of about 191,228 (312)
Identification of Novel Pigmentation Modulators by Chemical Genetic Screening [PDF]
Journal of Investigative Dermatology, 2007 There is a continual need for compounds that effectively modulate melanin synthesis. To identify novel pigmentation modulators and their cellular targets, chemical genetic screenings were performed with triazine-based combinatorial libraries that include various linkers as intrinsic components of the small molecules in the library.
Ni-Komatsu, Li, Orlow, Seth J.
openaire +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Biotropia: The Southeast Asian Journal of Tropical Biology, 2017 Multidrug-resistant (MDR) bacteria infections become a serious problem for these several decades. To solve this issue, finding of new antibiotics candidate in an urgency.
Mada Triandala Sibero +3 more
doaj +1 more source
Toward identification of larval sailfish (Istiophorus platypterus), white marlin (Tetrapturus albidus), and blue marlin (Makaira nigricans) in the western North Atlantic Ocean* [PDF]
, 2005 The identification of larval istiophorid billfishes from the western North Atlantic Ocean has long been problematic. In the present study, a molecular technique was used to positively identify 27 larval white marlin (Tetrapturus albidus), 96 larval blue ...
Cowen, Robert K. +3 more
core +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
HeritageHatchett’s Brown, also known as Van Dyck Rose, was a unique pigment used in the 19th century, discovered and described by Charles Hatchett in 1803. This article presents the results of research on the identification of this pigment in the works of Henryk
Anna Klisińska-Kopacz +1 more
doaj +1 more source
Plants, 2021 The Agrobacterium rhizogenes hairy root transformation system is widely used in symbiotic studies of model legumes. It typically relies on fluorescent reporters, such as DsRed, for identification of transgenic roots.
Yiting Ruan +5 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
HeritageImaging techniques have revolutionized cultural heritage analysis, particularly for objects that cannot be sampled. This study investigated the utilization of spectral imaging for the identification of pigments in artifacts from the Arxiu Valencià del ...
Álvaro Solbes-García +5 more
doaj +1 more source
Pigment identification with optical coherence tomography and multispectral imaging [PDF]
, 2008 We describe a new method for non-invasive pigment identification by combining the spectral reflectance in the visible spectrum with near infrared OCT cross-section images of the subsurface layer ...
Keita, K +3 more
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