Results 111 to 120 of about 88,097 (293)

Balancing Stealth and Targetability: cCPP‐ and PEG‐Modified Liposomes for the Targeted Delivery of Anti‐HER2 Nanobodies

open access: yesAdvanced Science, EarlyView.
This study addresses the rapid renal clearance of anti‐HER2 nanobodies by developing specialized liposomal carriers. It details the formulation of dual modified liposomes, demonstrating how PEGylation preserves structural integrity and cell‐penetrating peptides enhance cellular interaction.
Giulia Pander   +14 more
wiley   +1 more source

Dermoscopic image-analysis system: estimation of atypical pigment network and atypical vascular pattern

open access: yes, 2006
Early detection of melanoma is one of the greatest challenges of dermatologic practice today. A new diagnostic method, the "ELM 7 point checklist", defines a set of seven features, based on color and texture parameters, which describe the malignancy of a
PAOLILLO, Alfredo   +12 more
core   +1 more source

The moss Bryum argenteum var. muticum Brid. is well adapted to cope with high light in continental Antarctica [PDF]

open access: yes, 2012
The net photosynthetic rate (NP), chlorophyll fluorescence, carotenoid content and chlorophyll content of the cosmopolitan moss Bryum argenteum were measured in the field at Botany Bay, southern Victoria Land, continental Antarctica (77°S).
M. Schlensog   +11 more
core   +1 more source

Sulfated Cyclocarya Paliurus Polysaccharide Sorchestrates the Gut Microbiome to Mobilize a Host‐Derived 12‐HEPE Against Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
A sulfated polysaccharide (SCP) from Cyclocarya paliurus alleviates ulcerative colitis by reshaping the gut microbiome. This remodeled microbiota orchestrates the upregulation of the host‐derived lipid 12‐HEPE, which directly inhibits the TLR4/NF‐κB pathway to suppress inflammation.
Xianxiang Chen   +11 more
wiley   +1 more source

Trap Depth Modulation and Antenna Effect of Organic Ligands for Enhancing Rare‐Earth Long Persistent Luminescence

open access: yesAdvanced Science, EarlyView.
Different from the current research trends that mainly focus on optimizing a single color system, a universal organic–inorganic hybrid strategy is proposed, aiming to synergistically enhance the luminescent properties of red, green, and blue multi‐color inorganic long‐persistent phosphorescent materials by trap depth modulation and antenna effect of ...
Ting Tan   +7 more
wiley   +1 more source

Single‐Cell Annotation and Localization via Integrating Spatial Transcriptomics Maps the Mouse Ocular Atlas and RAO Dynamics

open access: yesAdvanced Science, EarlyView.
We developed the ASCAL pipeline, integrating complementary spatial transcriptomics, to construct a high‐fidelity mouse whole‐eye single‐cell atlas. Applying ASCAL to a retinal artery occlusion (RAO) model revealed spatially restricted immune activation localized to the ganglion cell layer and the selective depletion of a translationally active, outer ...
Chen Du   +11 more
wiley   +1 more source

Cellular interactions during zebrafish adult stripe formation and implications for pigment pattern evolution

open access: yes, 2014
Thesis (Ph.D.)--University of Washington, 2014Pigment patterns are among the most striking of traits, yet we know very little about the interactions required for organizing pigment cells during adult pattern formation or how evolutionary changes in ...
Patterson, Larissa Blythe
core  

The pugilistDominant Mutation of Drosophila melanogaster: A Simple-Sequence Repeat Disorder Reveals Localized Transport in the Eye.

open access: yesPLoS ONE, 2016
The pugilist-Dominant mutation results from fusion of a portion of the gene encoding the tri-functional Methylene Tetrahydrofolate Dehydrogenase (E.C.1.5.1.5, E.C.3.5.4.9, E.C.6.3.4.3) to approximately one kb of a heterochromatic satellite repeat ...
Yikang S Rong   +2 more
doaj   +1 more source

Sodium Ascorbate‐Accelerated Gelling Hydrogels With Rapid Self‐Mineralized Capacity for Chronic Wounds

open access: yesAdvanced Science, EarlyView.
An immunoregulatory hydrogel based on sodium ascorbate (SA)‐accelerated gelation and in situ self‐mineralization is prepared here. Such a hydrogel is constructed by mixing benzaldehyde‐ and cyanoacetate‐functionalized dextran with silver nitrate (AgNO3) and SA, enabling the ultrafast solidification and in situ self‐mineralization of silver ...
Xiaoya Ding   +4 more
wiley   +1 more source

Morpho-Functional Correlation in Pattern Dystrophy of the Retinal Pigment Epithelium

open access: yes, 2010
Purpose To evaluate the morpho-functional correlations in patients affected by pattern dystrophy (PD) of the retinal pigment epithelium. Methods The design of the study is a prospective observational case series.
P. Iacono   +6 more
core  

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