Results 41 to 50 of about 2,061,422 (300)
Genetics and Evolution of Pigment Patterns in Fish [PDF]
Pigment Cell Research, 2004 Vertebrate pigment patterns are both beautiful and fascinating. In mammals and birds, pigment patterns are likely to reflect the spatial regulation of melanocyte physiology, via alteration of the colour‐type of the melanin synthesized. In fish, however, pigment patterns predominantly result from positioning of differently coloured chromatophores ...
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Pigment dispersion syndrome and pigmented pattern dystrophy of retinal pigment epithelium. [PDF]
British Journal of Ophthalmology, 1983 The 2 rare entities, pigmentary dispersion syndrome and pigmented pattern dystrophy of the retinal pigment epithelium, were found in a young male patient. Visual function was undisturbed.
E Y, Chew, A F, Deutman
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PLoS Genetics, 2011 The pigment cells of vertebrates serve a variety of functions and generate a stunning variety of patterns. These cells are also implicated in human pathologies including melanoma.
Erine H Budi +2 more
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Biological effects of cigarette smoke in cultured human retinal pigment epithelial cells. [PDF]
, 2012 The goal of the present study was to determine whether treatment with cigarette smoke extract (CSE) induces cell loss, cellular senescence, and extracellular matrix (ECM) synthesis in primary human retinal pigment epithelial (RPE) cells. Primary cultured
Johannes Burger +8 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
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Long-term visual and microperimetry outcomes following autologous retinal pigment epithelium choroid graft for neovascular age-related macular degeneration [PDF]
, 2009 To describe the 2- to 4-year visual and microperimetry outcomes of autologous retinal pigment epithelium (RPE)-choroid graft in patients with neovascular age-related macular degeneration (AMD).In this retrospective cohort study, 12 patients with ...
Coffey, PJ +9 more
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Transcriptome-wide analysis reveals candidate genes responsible for the asymmetric pigment pattern in scallop Patinopecten yessoensis [PDF]
Invertebrate Survival Journal, 2016 Transcriptome-wide analysis reveals candidate genes responsible for the asymmetric pigment pattern in scallop Patinopecten yessoensis XJ Sun, LQ Zhou, ZH Liu, B Wu, AG Yang Yellow Sea Fisheries Research Institute, Chinese Academy of Fishery Sciences ...
XJ Sun, LQ Zhou, ZH Liu, B Wu, AG Yang
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Patterning Skin Pigmentation via Dickkopf [PDF]
Journal of Investigative Dermatology, 2007 One of the striking regional variations in skin is its pigmentation. Yamaguchi et al. further dissect the mechanism of regional pigmentation by assessing the effects of dickkopf 1 (DKK1), an antagonist of the Wnt pathway produced in lightly pigmented skin, on melanocyte gene expression. The results provide a plethora of candidate genes that may mediate
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Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
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