Results 181 to 190 of about 238,570 (350)

Refractive Index‐Corrected Light‐Sheet Microscopy for Macro‐View Cardiovascular Imaging

open access: yesAdvanced Science, EarlyView.
A refractive index‐corrected light‐sheet fluorescence microscopy system enables macro‐view cardiovascular imaging across organs, adapting to refractive index variations from different optical clearing protocols. By integrating axial sweeping, multi‐view imaging, and a sealed chamber, it extends the field of view, enhances isotropy, and improves safety.
Enbo Zhu   +13 more
wiley   +1 more source

Sleep Deprivation Activates a Conserved Lactate‐H3K18la‐RORα Axis Driving Neutrophilic Inflammation Across Species

open access: yesAdvanced Science, EarlyView.
Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou   +15 more
wiley   +1 more source

Physician burnout or joy: Rediscovering the rewards of a life in medicine,

open access: yesInternational Journal of Women's Dermatology, 2020
Pearl E. Grimes, MD
doaj  

PRC1‐Mediated H2Aub Loop Formation and Function in Arabidopsis

open access: yesAdvanced Science, EarlyView.
In the Arabidopsis genome, H2Aub and H3K27me3 marks do not always co‐localize, and some regions are marked exclusively by H2Aub. By using Capture‐Hi‐C, it is found that H2Aub loops are preferentially established between two H2Aub enriched regions.
Lingxiao Luo   +8 more
wiley   +1 more source

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