Results 221 to 230 of about 188,698 (303)

Age‐related differences in hydroxychloroquine‐associated adverse events: A pharmacovigilance study based on the FDA Adverse Event Reporting System

British Journal of Clinical Pharmacology, EarlyView.
Aims This real‐world pharmacovigilance study utilizes FDA Adverse Event Reporting System (FAERS) data (2004–2024) to characterize age‐related disparities in hydroxychloroquine (HCQ)‐associated adverse events (AEs), addressing gaps in age‐stratified risk assessment. Methods Disproportionality analysis (reporting odds ratios, RORs) and parametric Weibull
Guanghan Sun, Jingrong Yang, Lei Wan, Xia Xu, Jing Wang   +4 more
wiley   +1 more source

Evolution in arid environments: the role of betalains, succulence, and medullary bundles. [PDF]

New Phytol
Carruthers T, Brockington SF, Maeda HA, Stull GW, Walker-Hale N, Yang Y, Smith SA.   +6 more
europepmc   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Skin concerns and treatment seeking trends among patients visiting aesthetic clinics in Lahore, Pakistan. [PDF]

Pak J Med Sci
Arif MA, Kanwal S, Arif A.
europepmc   +1 more source

Ceftriaxone‐associated immune haemolytic anaemia: A patient‐level systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Ceftriaxone can cause acute haemolysis. Its clinical presentation, risk factors, and outcomes remain incompletely characterized. We conducted a systematic review of published cases with patient‐level data, following international guidelines and with registration in PROSPERO (CRD420261338709). Reports were identified through three bibliographic
Sonja Miotti, Giada Wyttenbach, Mario G. Bianchetti, Camilla Lavagno, Pietro Camozzi, Gregorio P. Milani, Renato Gualtieri, Sebastiano A. G. Lava, Pietro B. Faré, Simone Janett   +9 more
wiley   +1 more source

The genetic architecture of human skin pigmentation: evolution and adaptation across global populations. [PDF]

Front Genet
Bose A, Sengupta M, Maitra S, Bandyopadhyay AR, Schaschl H.   +4 more
europepmc   +1 more source

Deciphering Nazi Racial Sorting: The Challenges of Attempting a Big Data Approach

Berichte zur Wissenschaftsgeschichte, EarlyView.
In 2019 I started analyzing a large set of “race cards” preserved in the German Federal Archives (Bundesarchiv). These cards document anthropometric measurements performed by SS experts during WWII in the territories occupied by the Nazi regime. Applying a big data approach, my goal was to use those cards to study the inner dynamics of the racial ...
Amir Teicher
wiley   +1 more source

Development and optical characterization of a multilayered head phantom for optical brain monitoring. [PDF]

J Biomed Opt
Awad-Pérez K, Roldan M, Kyriacou PA.
europepmc   +1 more source

Machine Learning Models of Phase Contrast Images Predict Efficiency of Human Pluripotent Stem Cell Differentiation to Cardiomyocytes

Biotechnology and Bioengineering, EarlyView.
Human pluripotent stem cells were differentiated to cTnT+ cardiomyocytes and imaged throughout the process using phase contrast. We predicted differentiation efficiency (cTnT+ area) from phase contrast and compared model performance with a live‐cell cTnT‐GFP reporter.
Austin K. Feeney, Yaniv Ovadia, Aaron D. Simmons, Christian Elabd, Claire J. Peplinski, Frank Li, Sean P. Palecek   +6 more
wiley   +1 more source