Results 41 to 50 of about 5,960,249 (275)
Natural‐Inspired Engineered Microalgae With Selenium Enrichment Enabled Potent Anti‐Tumor Immunity
Advanced Science, EarlyView.Se‐Ssp was engineered as a potent immunomodulator for activating innate immunity via the TLR and cGAS‐STING pathways, therefore converting “cold” tumors into “hot” tumors to achieve high efficacy and long‐term therapeutic outcomes. ABSTRACT Immunotherapy has shed light on clinical oncology for several decades.
Yuqi Yang +11 more
wiley +1 more source
Pigmented Bowen’s disease presenting with a “starburst” pattern
Dermatology Practical & Conceptual, 2016 Pigmented Bowen’s disease (pBD) is an uncommon in situ squamous cell carcinoma of the skin usually presenting as a dark scaly plaque involving chronically exposed sites, which is not uncommonly mistaken for other similar pigmented lesions, such as ...
Maione Vincenzo +3 more
doaj +1 more source
Dermoscopy of basal cell carcinoma
, 2018 Dermoscopy is widely used in dermatological practice. The method increases the accuracy of basal cell carcinoma (BCC) detection. Pigmented and nonpigmented variants of basal cell carcinoma present different dermoscopic features.
Rudnicka, L. +5 more
core +1 more source
Advanced Science, EarlyView.BNC2 exhibits context‐dependent opposing functions across multiple cancer types. This study reveals BNC2 as an oncogenic driver of melanoma proliferation and metastasis through transcriptional activation of PIK3CA. The natural compound TSN simultaneously degrades BNC2 and its oncogenic partner SMAD3 via CRBN‐dependent ubiquitination.
Hui Dai +7 more
wiley +1 more source
Sclerodermiform basal cell carcinoma in an elderly woman
, 2023 The most commonly detected non-melacytic skin tumor in humans is "basal cell carcinoma". There are many clinical varieties of this tumor, some of which are quite rare.
Ekaterina V. Zadionchenko +1 more
core +1 more source
Accuracy of Dermatoscopy in the Diagnosis of Basal Cell Carcinoma on the Skin of Head and Neck
Advanced Medical Journal, 2023 Background and objectives: Basal cell carcinoma is the commonest malignancy among all malignancies of the body. Sun exposure plays an important role in its pathogenesis. Basal cell carcinoma usually is localized and metastasizes rarely.
Dindar Sharif Qurt, Rawa Karem Mama
doaj +1 more source
Advanced Science, EarlyView.An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu +10 more
wiley +1 more source
Pigmented poroma with unsusual locatin and dermatoscopic features
Dermatology Practical & Conceptual, 2012 Poroma is a benign adnexal neoplasm with “poroid”/ductal differentiation that mimics benign and malignant skin tumors. Histopathology shows circumscribed proliferation of poroid cells intermingled with a variable number of cuticular cells.
Luiza E.B.P. Kassuga +3 more
doaj +1 more source
Pigmented Lesions of Skin: A Histopathologic Experience at a Tertiary Care Center in Central Nepal
Journal of College of Medical Sciences-Nepal, 2021 Introduction Pigmented skin lesions refer to lesions that are brown, black or blue in color. These are not always melanocytic in origin. Keratinocytic, vascular or reactive pigmentation in other lesions can also appear pigmented.
Binita Goyal +3 more
doaj +1 more source
Animal Models and Experimental Medicine, EarlyView.Using F1 (C57BL/6J/Smad4+/− X CC) mice, we found that partial loss of Smad4 promotes liver carcinogenesis in a strain‐dependent manner, highlighting the importance of genetic modifiers in tumor susceptibility. The use of Collaborative Cross mice provides a valuable platform for uncovering genotype‐specific cancer susceptibilities in preclinical ...
Osayd Zohud +3 more
wiley +1 more source