Results 51 to 60 of about 5,960,249 (275)

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

British Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher, Amina Džidić‐Krivić, Emma Pinjic, Nejra Selak, Kanita Omerbasic, Alexandar Chupin, Andrej Belancic, Almir Fajkic   +7 more
wiley   +1 more source

Giant pigmented basal cell carcinoma in the inguinal region: A diagnostic challenge at an uncommon site [PDF]

Medical Laboratory Journal
Background: Basal cell carcinoma is the most common skin cancer. It accounts for 80% of all non-melanoma skin cancers. It most commonly occurs in sun-exposed areas. 0.094% of the cases occur in the inguinal region.
Vidhya Venkatesan, Jessica Minal, Nikhil Pudhu Veetil, Kanna Sandhyarani Mahadev, Archana Shetty   +4 more
doaj  

Linear adamantinoid basal cell carcinoma in the axilla [PDF]

, 2015
We present a case of asymptomatic deeply pigmented linear plaque with rolled borders that we encountered in an elderly Indian male over a sun protected site, the left axilla.
Bajaj, Sonali, Sharma, Prafulla Kumar, Kar, Hemanta Kumar, Sonali Bajaj, Hemanta Kumar Kar, Prafulla Kumar Sharma, Bajaj, Sonali ; Sharma, Prafulla Kumar ; Kar, Hemanta Kumar   +6 more
core   +1 more source

Micro‐ and nanoplastics in gastrointestinal disorders: Mapping the translational gap between exposure, biomonitoring, and pathogenic mechanisms

BMEMat, EarlyView.
This review highlights critical “translational gaps” in understanding micro‐ and nanoplastics impacts on gastrointestinal diseases, bridging exposure, detecting, and mechanistic toxicology. Abstract Micro‐ and nanoplastics (MNPs) have become pervasive environmental contaminants with increasing evidence linking them to adverse health outcomes.
Zhenli Diao, Yujie Luo, Chuanda Zhu, Yanwei Hu   +3 more
wiley   +1 more source

Basal cell carcinoma: a one-year study on the frequency of pathological types and related clinical factors [PDF]

Romanian Journal of Medical Practice
Background. Skin cancer is one of the most common cancers in Iraq and worldwide. Basal cell carcinoma (BCC) constitutes the majority of diagnosed skin cancers, accounting for approximately 80% of cases.
Mohammed Y. Abbas, Mohammed N. Hilmi, Haider S. Bedi   +2 more
doaj   +1 more source

Pigmented Bowen's disease of the penis and scrotum in a patient with AIDS [PDF]

, 2014
Patients with HIV have higher risk of developing squamous cell carcinoma of the skin given the increased risk of HPV infection, which alters cell proliferation and apoptosis [1]. Pigmented Bowen’s disease is an uncommon form of squamous cell carcinoma in-
Raslan, Wasim, Dawamneh, M Fawaz, Al-Dawsari, Najla A, M Fawaz Dawamneh, Najla A Al-Dawsari, Al-Dawsari, Najla A ; Raslan, Wasim ; Dawamneh, M Fawaz, Wasim Raslan   +6 more
core   +1 more source

Pumpkin and chia seeds as functional foods and their application in different food products: A review

Food Biomacromolecules, EarlyView.
Abstract Functional foods have gained increasing attention for their capacity to promote health and reduce chronic‐disease risk beyond basic nutrition. Among plant‐based functional ingredients, pumpkin (Cucurbita spp.) and chia (Salvia hispanica L.) seeds are nutrient‐dense sources of proteins, unsaturated fatty acids, dietary fiber, tocopherols ...
Fatima Urooj, Fatima Javed, Abdul Mueez Ahmad, Laiba Younas, Sadia Ansar, Sumbal Raana, Muhammad Abdullah, Rimsha Amjad, Kashaf Basharat   +8 more
wiley   +1 more source

Dermatoscopic Criteria of Non-pigmented Basal Cell Carcinoma

Львівський клінічний вісник, 2014
Introduction. Basal cell carcinoma is one of the most common malignant tumors, which accounts for about 75.0 % of all skin cancers. Despite the fact that the characteristic manifestations of BCC are fairly typical, different clinical sub-varieties can ...
Н. Кіладзе, Т. Шулаіа, А. Булінська, Л. Абрагамович   +3 more
doaj   +1 more source

Invasive basal cell carcinoma: A case report

, 2018
Basal cell carcinoma (BCC) is an epithelial tumor of low-grade malignancy, recurrent, with capacity for local invasion and destruction of adjacent bone or cartilage, yet rare metastasis.
Maria do Socorro Vieira Pereira, Jozinete Vieira Pereira, Daliana Queiroga de Castro Gomes, Myllena Alves Xavier, Henrique Cezar Coutinho Barsi Filho, Jadeilson de Moura Ferreira, Ernani Canuto Figueirêdo Júnior   +6 more
core   +1 more source

OXCT1‐driven succinylation of PSMG3 stabilizes the proteasome to facilitate picornavirus replication

iMetaOmics, EarlyView.
Upon entering the pig, foot‐and‐mouth disease virus (FMDV) regulates host glycolysis and the citrate cycle by modulating the expression of metabolic enzymes, resulting in changes in post‐translational modifications (PTMs) including succinylation, lactylation, crotonylation, acetylation, and phosphorylation.
Huisheng Liu, Qiao Xue, Pengfei Liu, Zhihua Dong, Weijun Cao, Fan Yang, Yingming Zhu, Lei Deng, Zixiang Zhu, Haixue Zheng   +9 more
wiley   +1 more source