Results 41 to 50 of about 553 (123)

When all you have is a dermatoscope—start looking at the nails

Dermatology Practical & Conceptual, 2014
Pigmented and non-pigmented nail alterations are a frequent challenge for dermatologists. A profound knowledge of clinical and dermatoscopic features of nail disorders is crucial because a range of differential diagnoses and even potentially life ...
Holger A. Haenssle, Andreas Blum, Rainer Hofmann-Wellenhof, Juergen Kreusch, Wilhelm Stolz, Giuseppe Argenziano, Iris Zalaudek, Franziska Brehmer   +7 more
doaj   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, Volume 2, Issue 2, April 2026.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

Robustness of a convolutional neural network trained on dermoscopic images and challenged with close‐up images

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 4, Page 504-513, April 2026.
Summary Background and Objectives Deep learning‐convolutional neural networks (DL‐CNNs) have demonstrated high diagnostic accuracy within the domain of dermoscopy. However, many clinical settings lack dermoscopic devices, requiring reliance on close‐up images. This study evaluates the robustness of a DL‐CNN trained on dermoscopic images when challenged
Anastasia Sophie Vollmer, Julia Katharina Winkler, Katharina Susanne Kommoss, Wilhelm Stolz, Albert Rosenberger, Alexander Enk, Holger Andreas Haenssle   +6 more
wiley   +1 more source

A Rare Case of Checkerboard-Like Becker Nevi with a Unique Distribution of Abnormalities

Case Reports in Dermatological Medicine, 2019
Becker nevus syndrome refers to a rare disorder comprising the typical pigmented lesion and its associated developmental abnormalities. Becker nevus itself is typically localized on the upper trunk, scapular or upper arm unilaterally; however, it can ...
Chanidapa Wongtada, Pravit Asawanonda, Marisa Pongprutthipan   +2 more
doaj   +1 more source

A 51‐year‐old female presenting with headache and vision loss

Headache: The Journal of Head and Face Pain, EarlyView.
Laurel Ovrom, Zachary Pardieck, Randy Christopher Bowen, Neena R. Cherayil   +3 more
wiley   +1 more source

Successful Treatment of Cutaneous Squamous Cell Carcinoma Complicated by Myelodysplastic Syndrome Using Combined ALA‐PDT and Narrow‐Margin Excision: A Case Report

Clinical Case Reports, Volume 14, Issue 3, March 2026.
ABSTRACT Cutaneous squamous cell carcinoma (cSCC) is the second most common type of non‐melanoma skin cancer. When the cSCC patient is complicated by myelodysplastic syndromes (MDS), treatment becomes particularly challenging due to immunosuppression, bleeding risk, and poor tolerance to conventional therapies.
Yunwei Yang, Zhenlin Li, Long Wen, Yongxian Lai, Guolong Zhang   +4 more
wiley   +1 more source

Progress on the Protective Effect and the Mechanism of Chinese Medicine Injection and Chinese Medicine Monomeric Small Molecules on Sepsis‐Related Liver Injury

Gut Medicine, Volume 2, Issue 1, Page 40-57, March 2026.
ABSTRACT Sepsis‐related liver injury (SRLI) involves multiple interrelated pathological processes, including excessive inflammation, oxidative imbalance, mitochondrial dysfunction, dysregulated autophagy, and microcirculatory impairment. Increasing evidence indicates that traditional Chinese medicine (TCM)–based interventions, particularly Chinese ...
Xiang Yunsheng, Yan Yumeng
wiley   +1 more source

Histopathological pattern of skin cancer at tertiary referral skin health centre

Journal of Pathology of Nepal, 2019
Background: The skin is a heterogeneous organ, capable of producing various types of skin tumors. The incidence of skin cancers, including melanoma and non-melanoma has been reported to have risen in many parts of the world.
Ram Chandra Adhikari, Mahesh Shah, Anil Kumar Jha   +2 more
doaj   +1 more source

Scalp Melanoma in a Young Patient With Systemic Sarcoidosis: Multidisciplinary Approach

Clinical Case Reports, Volume 14, Issue 2, February 2026.
ABSTRACT Often discovered at late stages, scalp melanoma presents unique diagnostic difficulties. Timely detection via public awareness, education, and comprehensive clinical assessment is essential for survival rate improvement. This case report shows the significance of multidisciplinary care and targeted therapies which can achieve remission even in
Nicolò Mori, Adriana Ključarić, Cristian Fidanzi, Filippo Fanetti, Chiara Carli, Rosanna Di Vita, Debora Serafin, Maria Oliveri, Luca Zatteri, Taiusha Fuentes, Fabiola Paiar, Riccardo Marconcini, Valerio Ortenzi, Cristian Scatena, Antonio Giuseppe Naccarato, Valentina Dini, Marco Romanelli, Agata Janowska   +17 more
wiley   +1 more source

An Algorithmic Dermatoscopic Approach to Non‑Pigmented Skin Tumors

Dermatology Practical & Conceptual
Introduction: Non-pigmented skin tumors represent a major diagnostic challenge in dermoscopy. In the absence of pigment, traditional pattern recognition is often unreliable, increasing the risk of misdiagnosis, particularly for melanoma and other ...
Aimilios Lallas, Giuseppe Argenziano
doaj   +1 more source