Results 121 to 130 of about 621,146 (257)

The Preparation of Novel Fluorenes Inspired by Hipposudoric Acid

open access: yesHelvetica Chimica Acta, EarlyView.
In this research we report on the design and synthesis of a series of fluorene‐based derivatives loosely inspired by the tricyclic framework of hipposudoric acid. Preparation of sixteen novel N‐alkylated derivatives was accomplished via a series of concise one‐step amide N‐alkylation reactions.
Munib Uddin   +3 more
wiley   +1 more source

DIFFERENTIAL DIAGNOSIS OF PIGMENTED CHOROIDAL LESIONS

open access: yes, 2014
Introduction. Pigmented lesions of the choroidal layer of the eye are challenging to diagnose, yet proper identification is critical due to the potential life-threatening risk of malignant melanoma.
Reed, Kimberly, Espejo, Alexandra
core   +1 more source

Lentigo Maligna of the Face: The Importance of Clinical, Dermoscopic, and Histological Correlation

open access: yesDermatology Practical & Conceptual, 2019
Giovana Serrão Fensterseifer   +4 more
doaj   +1 more source

Punch biopsy is best avoided for clinically suspicious pigmented lesions

open access: yes, 2019
Two patients had suspicious pigmented lesions that were partially punch biopsied by their primary care physicians, resulting in sampling error and subsequent pathology misdiagnosis.
Ciranni, Dominico   +2 more
core   +1 more source

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

open access: yesIbrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li   +10 more
wiley   +1 more source

Digital Dermoscopy analysis for automated diagnosis of pigmented skin lesions

open access: yes, 2002
Noninvasive diagnostic methods such as dermoscopy or epiluminescence light microscopy have been developed in an attempt to improve diagnostic accuracy of pigmented skin lesions.
BARBINI P.   +7 more
core   +1 more source

Second Breast‐Conserving Treatment for Ipsilateral Breast Tumor Recurrence: A Review of Patient Selection, Reirradiation Techniques, and Clinical Outcomes

open access: yesInternational Journal of Cancer, EarlyView.
ABSTRACT Local recurrence after primary breast cancer treatment remains a complex clinical scenario in patients previously treated with breast‐conserving therapy and radiotherapy. For decades, salvage mastectomy was considered the standard treatment for ipsilateral breast tumor recurrence, largely because of concerns about local control after repeat ...
Cezara Cheptea   +4 more
wiley   +1 more source

Assessment and management of dyspareunia in peri‐ and postmenopausal women: A phenotype‐based gynecologic approach

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Dyspareunia in peri‐ and postmenopausal women is common, clinically consequential, and often undertreated in gynecologic practice. Although genitourinary syndrome of menopause (GSM) is a frequent contributor, intercourse‐related pain may also reflect vestibular, pelvic floor, dermatologic, inflammatory, treatment‐related, and psychosocial ...
Marek Broul   +3 more
wiley   +1 more source

Dirty Looking Pigmented Lesions on Neck and Trunk. [PDF]

open access: yesIndian Dermatol Online J, 2023
Meghwal L, Balai M, Gupta LK.
europepmc   +1 more source

Dissecting the angiogenic mechanism of pachychoroid polypoidal choroidal vasculopathy

open access: yesiMeta, EarlyView.
A prognosis‐oriented classification system was established to distinguish Pachy PCV from Non‐pachy PCV using a large multicenter dataset. Comparative plasma multi‐omics profiling of Pachy PCV, Non‐pachy PCV, and normal controls revealed unique upregulation of the fluid shear stress and atherosclerosis (FSS‐AS) and HIF‐1 signaling pathways in Pachy PCV.
Xinyu Zhao   +18 more
wiley   +1 more source

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