Results 201 to 210 of about 1,355,599 (252)

Surgical removal of a perirectal melanoma through sphincterotomy and rectal wall resection in a horse

open access: yesEquine Veterinary Education, EarlyView.
Summary Melanomas are among the most frequent neoplasms in grey horses. Deep perirectal melanomas, however, are uncommon and challenging to excise due to their proximity to the peritoneal reflection. This report describes the successful standing removal of a large (16 × 8 × 6 cm) perirectal melanoma firmly adherent to the dorsal rectal wall in a 19 ...
R. Becker, C. Koch, M. de Preux
wiley   +1 more source

Detection of NTRK1/2/3 rearrangements in pigmented spindle cell naevus of Reed: a comparative study of optimized pan‐TRK immunohistochemistry, FISH and RNA‐NGS

open access: yesHistopathology, EarlyView.
Pigmented spindle cell nevus of Reed (PSCN) is a subtype of Spitz nevus mainly characterized by MYO5A::NTRK3 fusion. Our optimized pan‐TRK protocol stained 16/79 (20.3%) PSCNs (diffuse, granular, cytoplasmic staining of moderate intensity) and revealed high values of specificity (94.4%–96.2%) and positive predictive value (92.3%) for the detection of ...
Costantino Ricci   +19 more
wiley   +1 more source

Bakuchiol: From structural mimicry to systems‐level skin biology

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Convergent outcomes, divergent mechanisms: bakuchiol vs. retinol. Bakuchiol exhibits functional convergence with retinol in improving extracellular matrix integrity, epidermal differentiation and barrier function, while operating through distinct mechanisms.
Ratan K. Chaudhuri
wiley   +1 more source

Enhancing scar appearance: Results from a cosmetic clinical study on dexpanthenol‐containing silicone gel and massage ball in adults and children

open access: yesInternational Journal of Cosmetic Science, EarlyView.
This cosmetic clinical study demonstrates improvements in scar appearance associated with the use of a dexpanthenol‐containing silicone gel with an integrated massage ball in adults and children. Abstract Objective To evaluate changes in scar appearance and tolerability associated with 8 weeks of use of a test product comprising a topical dexpanthenol ...
Erwan Peltier   +3 more
wiley   +1 more source

Pretreatment of keratinocytes with Galactomyces ferment filtrate (GFF) promotes stress resiliency in an in vitro oxidative stress model

open access: yesInternational Journal of Cosmetic Science, EarlyView.
GFF pretreatment enhances keratinocyte protection against oxidative stress by mitigating stress‐induced biomolecular changes and gene expression dysregulation. GFF‐pretreated keratinocytes maintain healthy epidermal biology post‐stress, preserving mitochondrial function and proliferative capacity.
Lisa C. Green   +7 more
wiley   +1 more source

The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley   +1 more source

Expert Consensus on the Management of Hyperpigmentation Disorders in India: A Modified Delphi Study by the Pigmentary Disorders Society

open access: yesInternational Journal of Dermatology, EarlyView.
Delphi‐based expert consensus for diagnosis and management of common hyperpigmentation disorders in Indian dermatology practice, integrating evidence review, iterative voting, and consensus‐driven recommendations. ABSTRACT Hyperpigmentation disorders are prevalent in individuals with skin of color and are associated with considerable psychosocial ...
Rashmi Sarkar   +12 more
wiley   +1 more source

Basal cell carcinoma in dark skin: clinical and dermoscopy features. [PDF]

open access: yesAn Bras Dermatol
Valadares PJC   +3 more
europepmc   +1 more source

The Biological Basis of the Merlin CP‐GEP Assay: Integrin Signaling and Early Metastatic Competence in Cutaneous Melanoma

open access: yesInternational Journal of Dermatology, EarlyView.
Merlin CP‐GEP integrates mechanistic insights into a clinically actionable assay to predict SLN metastasis risk and inform personalized management of cutaneous melanoma. ABSTRACT The recent inclusion of the Merlin clinicopathologic–gene expression profile (CP‐GEP) assay in the National Comprehensive Cancer Network (NCCN) Melanoma Guidelines represents ...
Frank Z. Jing, Alexander Meves
wiley   +1 more source

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