Results 61 to 70 of about 1,355,599 (252)

Glutaminolysis Blockade‐Empowered Bimodal Nanodepot for Spatially Complementary Sono‐Thermal Ablation via PANoptosis and STING Activation Against Large Tumors

open access: yesAdvanced Science, EarlyView.
An injectable bimodal TCPD nanodepot disrupts glutaminolysis and TCA metabolism, sensitizing large tumors to spatially complementary sono‐thermal ablation for complete treatment coverage. This intervention induces mitochondrial and endoplasmic reticulum dysfunction, genotoxicity, and NAD+ depletion, converging to trigger PANoptosome assembly and ...
Yi‐Ming Liu   +10 more
wiley   +1 more source

Multiple Pigmented Bowen’s Disease: A Diagnostic and Therapeutic Dilemma

open access: yesCase Reports in Oncological Medicine, 2012
Bowens' disease (BD) is a precancerous condition of skin and/or mucosa with a predilection towards sun-exposed areas. Extensive literature research failed to reveal any case of multiple pigmented BD in type V Fitzpatrick skin.
Pratik Gahalaut   +3 more
doaj   +1 more source

Design and validation of a new machine-learning-based diagnostic tool for the differentiation of dermatoscopic skin cancer images.

open access: yesPLoS ONE, 2023
BackgroundSkin cancer is the most common cancer in the United States. Current estimates are that one in five Americans will develop skin cancer in their lifetime.
Amin Tajerian   +3 more
doaj   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

open access: yesAdvanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li   +9 more
wiley   +1 more source

Dermoscopy of pigmented skin lesions.

open access: yes, 2005
Dermoscopy is an in vivo method for the early diagnosis of malignant melanoma and the differential diagnosis of pigmented lesions of the skin. It has been shown to increase diagnostic accuracy over clinical visual inspection in the hands of experienced ...
Oliviero M   +4 more
core   +1 more source

Video‐Assisted Intralesional Curettage for Invasive Nonmalignant Giant Cell Tumors

open access: yesArthroscopy Techniques, EarlyView.
Abstract Giant cell tumor of bone is a locally aggressive benign neoplasm with a strong tendency for local recurrence after surgical treatment. Intralesional excision and curettage is preferred in most cases to maximize tumor removal while preserving the affected joint.
George Loria   +5 more
wiley   +1 more source

Topical treatment of skin lesions

open access: yes, 2021
hello,My thesis describes skin lesions in different types of diseases and the topical treatment involvedáltalános orvosmagyaregységes ...
Katz, Amit
core  

Biomaterials for modulating cellular responses of endogenous tendon stem/progenitor cells: A promising avenue for tendon regeneration

open access: yesBMEMat, EarlyView.
This review comprehensively summarizes emerging biomaterial‐based strategies and underlying mechanisms for modulating endogenous tendon stem/progenitor cells (TSPCs). It offers the most recent insights into TSPC physiology and potential applications of tissue engineering and regenerative medicine in tendons.
Zeyu Zhu   +9 more
wiley   +1 more source

Avaliação de lesões melanocíticas através da dermatoscopia [PDF]

open access: yes, 2010
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Medeiros, Amanda Cochilar
core  

Patterns of dermoscopy in common pigmented skin lesions

open access: yes, 2018
Objective To describe predominant dermoscopic patterns in common pigmented skin lesions in skin of colour. Methods It was an observational study carried out at department of dermatology unit-II, Mayo Hospital Lahore.
Aneela Asghar   +3 more
core   +1 more source

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