Results 11 to 20 of about 110,203 (267)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Preparation and Characterization of Some Hyperbranched Polyesteramides/Montmorillonite Nanocomposites

International Journal of Polymer Science, 2013
Different polyesteramides hyperbranched polymers (HPEA1-6)/montomorillonite clay (MMT) nanocomposites were prepared with three different loading contents of clay (4, 10, and 15 wt%).
Amal Amin, Moshera Samy
doaj   +1 more source

Sustainable reverse osmosis thin-film composite membranes based on cellulose acetate and recycled acrylic fiber waste

Applied Water Science
Thin-film composite reverse osmosis (RO) membranes were developed using recycled acrylic fiber waste as a sustainable support material and cellulose acetate (CA) as the selective layer.
Ahmed E. Abdelhamid, Alaa Eldesoky Elsayed, Eman AboBakr Ali   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Insight on the impact of Acacia nilotica leaves extract on the characteristics of natural and synthetic rubber composites

Scientific Reports
The purpose of this study is to assess the extract of Acacia nilotica leaves as a sustainable natural antioxidant for natural rubber (NR) and styrene-butadiene rubber (SBR) composites.
T. A. Zidan, Sayed A. El-Toumy, M. N. Ismail, D. E. El-Nashar, A. I. Khalaf   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Evaluating Provitamin A Carotenoids and Polar Metabolite Compositions during the Ripening Stages of the Agung Semeru Banana (Musa paradisiaca L. AAB)

International Journal of Food Science, 2020
Banana cultivars that are rich in provitamin A carotenoids and other nutrients may offer a potential food source to help alleviate vitamin A deficiencies, particularly in developing countries.
Rosita D. Chandra, Chandra A. Siswanti, Monika N. U. Prihastyanti, Heriyanto, Leenawaty Limantara, Tatas H. P. Brotosudarmo   +5 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Rheological, mechanical, and cytotoxic properties of sustainable NR/glass fiber composites: prospects for advanced applications

BMC Chemistry
Glass fiber is an inorganic reinforcement material widely used in rubber-based technological products. This study investigates the properties of natural rubber/glass fiber composites, focusing on their potential to enhance mechanical performance while ...
Doaa S. Mahmoud, Abdelmohsen M. Soliman, Fahima M. Helaly, Salwa H. El-Sabbagh   +3 more
doaj   +1 more source