Results 201 to 210 of about 1,468,747 (408)

Allosteric Modulation of Pathological Ataxin‐3 Aggregation: A Path to Spinocerebellar Ataxia Type‐3 Therapies

Advanced Science, EarlyView.
This study uncovers a new allosteric site in the Josephin domain of ataxin‐3 targeted by the molecular tweezer CLR01, which modulates protein aggregation, improves synaptic function in neuronal cells, and delays motor dysfunction in animal models.
Alexandra Silva, Sara Duarte‐Silva, Pedro M. Martins, Beatriz Rodrigues, Débora Serrenho, Daniela Vilasboas‐Campos, Andreia Teixeira‐Castro, Julio Vieyto‐Nuñez, Joel Mieres‐Perez, Francisco Figueiredo, Martyna Podlasiak, Tatiana Van‐der‐Kellen, Joana Fraga, James Noble, Carter Lantz, Niki Sepanj, Daniela Monteiro‐Fernandes, Sara Guerreiro, Andreia Neves‐Carvalho, Joana Pereira‐Sousa, Frank‐Gerrit Klärner, Thomas Schrader, Joseph A. Loo, Annalisa Pastore, Elsa Sanchez‐Garcia, Gal Bitan, Ana Luísa Carvalho, Patrícia Maciel, Sandra Macedo‐Ribeiro   +28 more
wiley   +1 more source

Isolation of porcine intestinal Lactobacillus salivarius and antimicrobial potential of its biosurfactant

BMC Veterinary Research
Background Lactobacillus salivarius (L. salivarius) is a probiotic widely colonized in the gastrointestinal tracts of humans and animals. Its biosurfactant (BS) exhibits antibacterial and antiviral activities, along with advantages such as ...
Xiaotian Zhou, Jing Ren, Chen Yuan, Feiyan Wang, Ligong Chen, Xiaobo Wang, Liu Yang, Lizhi Fu, Qinye Song   +8 more
doaj   +1 more source

Reaction of Hypochlorous Acid with Bovine Nasal Cartilage Comparison to Pig Articular Cartilage [PDF]

, 1997
Jürgen Schiller, Jürgen Arnhold, Annett Zachäus, Arnold Klaus   +3 more
openalex   +1 more source

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

Advanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen, Houcheng Li, Jinyan Teng, Zhen Wang, Xiaolu Qu, Zhe Chen, Xiaodian Cai, Haonan Zeng, Zhonghao Bai, Jinghui Li, Xiangchun Pan, Leyan Yan, Fei Wang, Lin Lin, Yonglun Luo, Goutam Sahana, Mogens Sandø Lund, Maria Ballester, Daniel Crespo‐Piazuelo, Peter Karlskov‐Mortensen, Merete Fredholm, Alex Clop, Marcel Amills, Crystal Loving, Christopher K. Tuggle, Ole Madsen, Jiaqi Li, Zhe Zhang, George E. Liu, Jicai Jiang, Lingzhao Fang, Guoqiang Yi   +31 more
wiley   +1 more source

Nutritional and energetic value of rice by-products, with or without phytase, for growing pigs [PDF]

, 2015
Julio Cezar Dadalt, Andréa Machado Leal Ribeiro, Alexandre de Mello Kessler, William Rui Wesendonck, Luciane Bockor, Gilson Alexandre Gomes   +5 more
openalex   +1 more source

Vitamin D Regulates Olfactory Function via Dual Transcriptional and mTOR‐Dependent Translational Control of Synaptic Proteins

Advanced Science, EarlyView.
Vitamin D (VitD) modulates olfactory function by remodeling dendrodendritic synapses in tufted cells through vitamin D receptor‐dependent transcriptional and translational mechanisms. VitD regulates synaptic protein translation partially via mTOR signaling.
Pengcheng Ren, Renhe Cao, Xiaoshan Ye, Wenbin Pang, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Wei Xiang, Le Xiao   +9 more
wiley   +1 more source

Sensitivity of guinea‐pig hippocampal granule cell field potentials to hexoses in vitro: an effect on cell excitability?

, 1984
H. S. Bachelard, D.W.G. Cox, J. Drower
openalex   +2 more sources

Morphological development of the testicles and spermatogenesis in guinea pigs (Cavia porcellus Linnaeus, 1758) [PDF]

, 2017
A. Nunes, Jorge Santos, Beatriz Tomé Gouveia, Victória Sabbado Menezes, M.H.T. Matos, Marcelo Domingues de Faria, Adriana Gradela   +6 more
openalex   +1 more source

Update on Mycoplasma hyopneumoniae infections in pigs: Knowledge gaps for improved disease control

Transboundary and Emerging Diseases, 2018
Dominiek Maes, M. Sibila, Peter Kuhnert, Joaquim Segalés, F. Haesebrouck, M. Pieters   +5 more
semanticscholar   +1 more source

Smart Hydrogel Doped by Metal–Organic Frameworks for Renewable Self‐Pumping Enzymatic Reactors

Advanced Science, EarlyView.
Renewable self‐pumping enzymatic reactors based on thermo‐stimulated cyclic contraction/expansion of metal‐organic frameworks‐doped hydrogel. Abstract The construction of high‐performance immobilized enzymes is vastly desired for green biotransformation.
Yuxi Zhu, Shenghao Wang, Yueyuan Luo, Linbo Cao, Xiuxiu Guo, Yue Zhang, Mingmin Li, Tie Wang   +7 more
wiley   +1 more source