Results 71 to 80 of about 20,835 (311)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Advances in Civil Engineering, 2019 To study the settlement and deformation characteristics of a long-short pile composite foundation and its influencing factors, the indoor centrifuge model test and numerical simulations were performed under the actual working conditions to treat the ...
Wei Liu +4 more
doaj +1 more source
ANALYSIS OF PILED RAFT FOUNDATIONS IN CLAYEY SOILS USING FINITE ELEMENT AND ANALYTICAL METHODS [PDF]
, 2013 Raft foundation may cause excessive settlement although it has an adequate bearing capacity. Using the combination of raft and pile foundation as named piled raft foundation system may be considered as the good alternative solution for this problem. This
WULANDARI, P., Wulandari, Paravita Sri
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Piles for offshore wind turbines: A state of the art review [PDF]
, 2012 The paper considers the current state of the art for estimating the pull-out capacity of driven open-ended piles used to support wind turbine foundations founded on sand.
Igoe, David +2 more
core +1 more source
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Load and Settlement of Pile-Raft Foundation at Post Consolidation from 3D FEM Analysis [PDF]
, 2016 Load and settlement behaviors of a numerical pile-raft foundation in soft soils after the consolidation are presented in this paper. Modified Cam Clay (MCC) model was adopted to model the soil behaviors.
Chang, Der-Wen;Lin, Wei-Chen;Liu, C.H.;Lu, Chih-Wei
core
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Nonlinear analysis of pile foundation jacket platform [PDF]
, 1997 In this paper, the nonlinear collapse of the BOHAI-8 pile foundation jacket platform has been analyzed. The ultimate load and collapse process of two computational models of the structure are given.
许滨 +2 more
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source