Results 41 to 50 of about 13,437 (268)
Response of group piles subjected to coupled vertical-eccentric lateral-seismic loads
Results in EngineeringIn seismic prone regions, analyzing loaded pile groups can be challenging because of limitations in conventional design methods and the inability of small-scale laboratory tests to accurately replicate the real behavior.
Duaa Al-Jeznawi +6 more
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Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Influence of Pile Spacing on the Compressive Bearing Performance of CEP Groups
BuildingsPile spacing is an important factor affecting the bearing capacity of concrete expansion pile (CEP) groups. In this study, a pile group was simulated and analyzed using ANSYS software R19.0.
Yongmei Qian +4 more
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Simplified analysis of laterally loaded pile groups
Alexandria Engineering Journal, 2012 The response of laterally loaded pile groups is a complicated soil–structure interaction problem. Although fairly reliable methods are developed to predicate the lateral behavior of single piles, the lateral response of pile groups has attracted less ...
F.M. Abdrabbo, K.E. Gaaver
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FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
南方能源建设[Introduction] The offshore wind power industry is among the most pioneering and strategic emerging sectors in the global development of new energy sources.
Weihua YANG +4 more
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Lateral capacity and deformations of vertical piles loaded by horizontal forces [PDF]
Građevinski Materijali i Konstrukcije, 2018 Pile foundations are frequently loaded by horizontal forces. In such cases, it is important to calculate lateral capacity of vertical piles. It is governed by the strength of the surrounding soil i.e. geotechnical capacity or pile strength parameters i.e.
Ćorić Slobodan +3 more
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