Results 51 to 60 of about 92,611 (307)

Model test on the axial capacity of displacement ribbed piles [PDF]

, 2016
The capacity, hence the load-settlement behaviour of a pile is governed by the collective behaviour of the base and shaft. It is highly desirable, sustainable and economical to accommodate the increasing demand for deeper and wider foundations through ...
A. Rashid, Ahmad Safuan, Ganiyu, Abideen Adekunle, Osman, Mohd. Hanim   +2 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

A study on stryi-icnos potatorum and pisum sativum as natural coagulants for meat food processing wastewater [PDF]

, 2018
Slow maintained load test is widely used by contractors in Malaysia to ensure the driven pile could accommodate the design load of the structure. Slow maintained load test is a test to determine load-settlement curve and pile capacity for a period of ...
Pahazri, Nor Fadzilah
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Effect of Pile Spacing on Load Bearing Performance of NT-CEP Pile Group Foundation

Buildings
The NT-CEP pile is an innovative type of pile that builds upon the conventional concrete straight-hole cast-in-place pile. It primarily consists of two components: the main pile and the bearing plate. The key factors influencing its load-bearing capacity
Yongmei Qian, Hualong Li, Wei Tian, Hang Yu, Yingtao Zhang, Ming Guan, Zhongwei Ma   +6 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The resumptive pile load capacity equation soils [PDF]

Строительство уникальных зданий и сооружений, 2014
The article is devoted to different formulas, describing the equation of pile load capacity. The most part of current building projects, ranging from country houses to high-rise building, utilizes various types of pile foundations. Today exists a broad
Georgiy Yakovlevich Bulatov, Ekaterina Igorevna Lysyakova, Marina Anatoljevna Korenevskaya   +2 more
doaj  

Perbandingan Kapasitas Dukung Aksial Pondasi Tiang Tunggal dengan Beberapa Metode Analisis (Studi Kasus : Pondasi Rumah Sakit Pendidikan Universitas Riau Pekanbaru) [PDF]

, 2014
A pile foundation design should be done carefully and as carefully as possible. Each foundation must be able to support loads up to the limit safely, including supporting the maximum load that may occur.
Muhardi, M. (Muhardi), Sanjaya, G. (Gigih), Satibi, S. (Syawal)   +2 more
core  

Insights into a long life without cancer: The case of the bowhead whale

Molecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source