Results 101 to 110 of about 479,217 (327)

Run 2 Upgrades to the CMS Level-1 Calorimeter Trigger [PDF]

open access: yes, 2015
The CMS Level-1 calorimeter trigger is being upgraded in two stages to maintain performance as the LHC increases pile-up and instantaneous luminosity in its second run.
Aggleton, R.   +63 more
core   +4 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

open access: yesFEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel   +8 more
wiley   +1 more source

Influence of Pile Spacing on the Compressive Performance and Soil Failure Mechanism of CEP Double Piles

open access: yesInfrastructures
Concrete expanded-plate piles (CEP piles) are novel variable-section piles that offer broader applicability, greater bearing capacity, and superior economic benefits compared to conventional straight-shaft piles.
Yongmei Qian   +6 more
doaj   +1 more source

Cost-Savings of Implementing Site-Specific Ground Motion Response Analysis in Design of Mississippi Embayment Bridges [PDF]

open access: yes, 2017
Deep dynamic site characterization and a site-specific ground motion response analysis (SSGMRA) were conducted for a bridge site in Monette, Arkansas.
Baker, Ethan Ryan Benton
core   +2 more sources

Topology of large-scale engineering problem-solving networks [PDF]

open access: yes, 2004
The last few years have led to a series of discoveries that uncovered statistical properties that are common to a variety of diverse real-world social, information, biological, and technological networks.
Bar-Yam, Yaneer, Braha, Dan
core   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

The Peierls--Nabarro FE model in two-phase microstructures -- a comparison with atomistics

open access: yes, 2020
This paper evaluates qualitatively as well as quantitatively the accuracy of a recently proposed Peierls--Nabarro Finite Element (PN-FE) model for dislocations by a direct comparison with an equivalent molecular statics simulation.
Bormann, F.   +3 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Association of Corticospinal Tract Asymmetry With Ambulatory Ability After Intracerebral Hemorrhage

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ambulatory ability after intracerebral hemorrhage (ICH) is important to patients. We tested whether asymmetry between ipsi‐ and contra‐lesional corticospinal tracts (CSTs) assessed by diffusion tensor imaging (DTI) is associated with post‐ICH ambulation.
Yasmin N. Aziz   +25 more
wiley   +1 more source

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